1quu Summary



The structure was published by Djinovic-Carugo, K., Young, P., Gautel, M., and Saraste, M., in 1999 in a paper entitled "Structure of the alpha-actinin rod: molecular basis for cross-linking of actin filaments." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.5 Å and deposited in 1999.

The experimental data on which the structure is based was not deposited.

The PDB entry contains the structure of HUMAN SKELETAL MUSCLE ALPHA-ACTININ 2. This molecule has the UniProt identifier P35609 (ACTN2_HUMAN)search. The sample contained 250 residues which is < 90% of the natural sequence. Out of 250 residues 248 were observed and are deposited in the PDB.

The molecule most likely forms homodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A HUMAN SKELETAL MUSCLE ALPHA-ACTININ 2 P35609 (391-637) (ACTN2_HUMAN)search Homo sapienssearch < 90% 250 99%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P35609 (391 - 637) HUMAN SKELETAL MUSCLE ALPHA-ACTININ 2 Homo sapiens

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A Spectrin repeatsearch Methane Monooxygenase Hydroxylase; Chain G, domain 1search Spectrin repeatsearch
Chain InterPro annotation
A Spectrin repeatsearch Spectrin/alpha-actininsearch