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EBI PDBe PDBeView

PDBe Entry: 1qsg view

CRYSTAL STRUCTURE OF ENOYL REDUCTASE INHIBITION BY TRICLOSAN
Summary
Header OXIDOREDUCTASEsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 1.75 Å, R-factor: 17.2%, Free R-factor: 21.5%, Spacegroup: P 1
Released 21/07/1999, deposition: 21/06/1999, last revision: 24/02/2009
Authors Stewart, M.J.search; Parikh, S.search; Xiao, G.search; Tonge, P.J.search; Kisker, C.search
Primary citation Structural basis and mechanism of enoyl reductase inhibition by triclosan.
J.MOL.BIOL.search vol:290, pag:859-865 (1999) [PubMed ID 10398587 ]search
Keywords ENOYL REDUCTASEsearch, OXIDOREDUCTASEsearch
EC 1.3.1.9 ExPASy BRENDA search (A B C D E F G H)
Organism Escherichia coli 562search(A B C D E F G H)
UniProt Enoyl-[acyl-carrier-protein] reductase [NADH] (EC 1.3.1.9) (NADH-dependent enoyl-ACP reductase) P0AEK4search (A B C D E F G H)
Solvent A, B, C, D, E, F, G, H
Related entries 1dfi, 1dfg, 1dfh
Polymers
Id Name Type UniProt Residues Observed
A, B, C, D, E, F, G, H ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE Protein P0AEK4 (FABI_ECOLI)search
 265 97%
Heterogens
Id Name Ligands
A, B, C, D, E, F, G, H SUGAR (GLUCOSE) GLC search
A, B, C, D, E, F, G, H NICOTINAMIDE-ADENINE-DINUCLEOTIDE NAD search
A, B, C, D, E, F, G, H TRICLOSAN TCL search
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