1qry Summary

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Homeobox protein VND (ventral nervous system defective protein)

The structure was published by Hwang, K.J., Xiang, B., Gruschus, J.M., et al., No, K.T., Nirenberg, M., and Ferretti, J.A., in 2003 in a paper entitled "Distortion of the three-dimensional structure of the vnd/NK-2 homeodomain bound to DNA induced by an embryonically lethal A35T point mutation." (abstract).

The structure was determined using NMR spectroscopy and deposited in 1999.

The experimental data on which the structure is based was not deposited.

The PDB entry contains the structure of PROTEIN (HOMEOBOX VENTRAL NERVOUS SYSTEM DEFECTIVE PROTEIN). This molecule has the UniProt identifier P22808 (VND_DROME)search. The sample contained 80 residues which is < 90% of the natural sequence. Out of 80 residues 80 were observed and are deposited in the PDB.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A PROTEIN (HOMEOBOX VENTRAL NERVOUS SYSTEM DEFECTIVE PROTEIN) P22808 (538-613) (VND_DROME)search Drosophila melanogastersearch < 90% 80 100%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P22808 (538 - 613) PROTEIN (HOMEOBOX VENTRAL NERVOUS SYSTEM DEFECTIVE PROTEIN) Drosophila melanogaster

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A Homeodomainsearch Homeodomain-likesearch Homeobox domainsearch

Chain ID Molecular function (GO)
A (P22808) DNA bindingsearch

Chain InterPro annotation
A Homeobox domainsearch Homeodomain-likesearch Homeodomain, metazoasearch