1qmh Summary

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Crystal structure of RNA 3'-terminal phosphate cyclase, an ubiquitous enzyme with unusual topology

The structure was published by Palm, G.J., Billy, E., Filipowicz, W., and Wlodawer, A., in 2000 in a paper entitled "Crystal Structure of RNA 3'-Terminal Phosphate Cyclase, a Ubiquitous Enzyme with Unusual Topology" (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.1 Å and deposited in 1999.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of RNA 3'-TERMINAL PHOSPHATE CYCLASE.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms homodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A RNA 3'-TERMINAL PHOSPHATE CYCLASE P46849 (2-338) (RTCA_ECOLI)search Escherichia coli K-12search 100% 347 96%
B RNA 3'-TERMINAL PHOSPHATE CYCLASE P46849 (2-338) (RTCA_ECOLI)search Escherichia coli K-12search 100% 347 96%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P46849 (2 - 338) RNA 3'-TERMINAL PHOSPHATE CYCLASE Escherichia coli K-12

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B (P46849) RNA 3'-terminal phosphate cyclase, RPTC, insert domainsearch, RNA 3'-terminal phosphate cyclase, RPTCsearch UDP-n-acetylglucosamine1-carboxyvinyl-transferase; Chainsearch, Dihydrodipicolinate Reductase; domain 2search PF01137: RNA 3'-terminal phosphate cyclasesearch

Chain ID Molecular function (GO) Biological process (GO) Cellular component (GO)
A, B (P46849) catalytic activitysearch RNA-3'-phosphate cyclase activitysearch nucleotide bindingsearch ligase activitysearch ATP bindingsearch RNA processingsearch cytoplasmsearch

Chain InterPro annotation
A, B RNA 3'-terminal phosphate cyclasesearch RNA 3'-terminal phosphate cyclase, insert domainsearch RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/betasearch RNA 3'-terminal phosphate cyclase type 1search RNA 3'-terminal phosphate cyclase-like, conserved sitesearch RNA 3'-terminal phosphate cyclase domainsearch