1qmf Summary



The structure was published by Gordon, E.J., Mouz, N., Duee, E., and Dideberg, O., in 2000 in a paper entitled "The Crystal Structure of the Penicillin Binding Protein 2X from Streptococcus Pneumoniae and its Acyl-Enzyme Form: Implication in Drug Resistance" (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.8 Å and deposited in 1999.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of PENICILLIN-BINDING PROTEIN 2X. This molecule has the UniProt identifier P14677 (PBPX_STRPN)search. The sample contained 702 residues which is 94% of the natural sequence. Out of 702 residues 558 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A PENICILLIN-BINDING PROTEIN 2X P14677 (49-750) (PBPX_STRPN)search Streptococcus pneumoniae TIGR4search 90% 702 79%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P14677 (49 - 750) PENICILLIN-BINDING PROTEIN 2X Streptococcus pneumoniae

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P14677) Penicillin-binding protein 2x (pbp-2x), c-terminal domainsearch, Penicillin binding protein dimerisation domainsearch, beta-Lactamase/D-ala carboxypeptidasesearch Penicillin-binding protein 2a (Domain 2)search, DD-peptidase/beta-lactamase superfamilysearch PF00905: Penicillin binding protein transpeptidase domainsearch, PF03717: Penicillin-binding Protein dimerisation domainsearch, PF03793: PASTA domainsearch

Chain ID Biological process (GO) Cellular component (GO) Molecular function (GO)
A (P14677) cell cyclesearch peptidoglycan biosynthetic processsearch response to antibioticsearch regulation of cell shapesearch cell divisionsearch cell wall organizationsearch plasma membranesearch membranesearch integral component of membranesearch penicillin bindingsearch

Chain InterPro annotation
A Penicillin-binding protein, transpeptidasesearch Penicillin-binding protein, dimerisation domainsearch PASTA domainsearch Beta-lactamase/transpeptidase-likesearch