1qlk Summary



The structure was published by Drohat, A.C., Baldisseri, D.M., Rustandi, R.R., and Weber, D.J., in 1998 in a paper entitled "Solution structure of calcium-bound rat S100B(betabeta) as determined by nuclear magnetic resonance spectroscopy,." (abstract).

The structure was determined using NMR spectroscopy and deposited in 1997.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of S-100 PROTEIN.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms homodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A S-100 PROTEIN P04631 (1-92) (S100B_RAT)search Rattus norvegicussearch 99% 92 100%
B S-100 PROTEIN P04631 (1-92) (S100B_RAT)search Rattus norvegicussearch 99% 92 100%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P04631 (1 - 92) S-100 PROTEIN Rattus norvegicus

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B (P04631) S100 proteinssearch EF-handsearch PF01023: S-100/ICaBP type calcium binding domainsearch

Chain ID Molecular function (GO) Cellular component (GO) Biological process (GO)
A, B (P04631) calcium ion bindingsearch protein homodimerization activitysearch protein bindingsearch tau protein bindingsearch zinc ion bindingsearch identical protein bindingsearch receptor bindingsearch metal ion bindingsearch RAGE receptor bindingsearch S100 protein bindingsearch calcium-dependent protein bindingsearch nucleussearch perinuclear region of cytoplasmsearch cytoplasmsearch neuronal cell bodysearch extracellular spacesearch rufflesearch learning or memorysearch memorysearch positive regulation of apoptotic processsearch positive regulation of synaptic transmissionsearch response to glucocorticoidsearch response to methylmercurysearch cellular response to hypoxiasearch positive regulation of cell proliferationsearch regulation of cell shapesearch positive regulation of I-kappaB kinase/NF-kappaB signalingsearch regulation of neuronal synaptic plasticitysearch long-term synaptic potentiationsearch negative regulation of skeletal muscle cell differentiationsearch astrocyte differentiationsearch

Chain InterPro annotation
A, B S100/Calbindin-D9k, conserved sitesearch EF-hand domainsearch EF-hand domain pairsearch S100/CaBP-9k-type, calcium binding, subdomainsearch EF-Hand 1, calcium-binding sitesearch Protein S100-Bsearch