MUTANT ESTROGEN NUCLEAR RECEPTOR LIGAND BINDING DOMAIN COMPLEXED WITH ESTRADIOL
The structure was published by Gangloff, M., Ruff, M., Eiler, S., Duclaud, S., Wurtz, J.M., and Moras, D., in 2001 in a paper entitled "Crystal Structure of a Mutant Heralpha Ligand- Binding Domain Reveals Key Structural Features for the Mechanism of Partial Agonism" (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.2 Å and deposited in 1999.
The experimental data on which the structure is based was also deposited.
The PDB entry contains the structure of ESTRADIOL RECEPTOR. This molecule has the UniProt identifier P03372 (ESR1_HUMAN). The sample contained 248 residues which is < 90% of the natural sequence. Out of 248 residues 248 were observed and are deposited in the PDB.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule most likely forms homodimers.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: