1qho Summary



The structure was published by Dauter, Z., Dauter, M., Brzozowski, A.M., et al., Beier, L., Wilson, K.S., and Davies, G.J., in 1999 in a paper entitled "X-ray structure of Novamyl, the five-domain "maltogenic" alpha-amylase from Bacillus stearothermophilus: maltose and acarbose complexes at 1.7A resolution." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 1.7 Å and deposited in 1999.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of ALPHA-AMYLASE. This molecule has the UniProt identifier P19531 (AMYM_GEOSE)search. The sample contained 686 residues which is < 90% of the natural sequence. Out of 686 residues 686 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A ALPHA-AMYLASE P19531 (34-253) (AMYM_GEOSE)search ,
P19531 (257-384) (AMYM_GEOSE)search ,
P19531 (387-719) (AMYM_GEOSE)search
Geobacillus stearothermophilussearch ,
Geobacillus stearothermophilussearch ,
Geobacillus stearothermophilussearch
< 90% ,
< 90% ,
< 90%
686 100%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P19531 (34 - 253) ALPHA-AMYLASE Geobacillus stearothermophilus

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A Amylase, catalytic domainsearch, E-set domains of sugar-utilizing enzymessearch, Starch-binding domainsearch, alpha-Amylases, C-terminal beta-sheet domainsearch Glycosidasessearch, Golgi alpha-mannosidase IIsearch, Immunoglobulinssearch Alpha amylase, catalytic domainsearch, Starch binding domainsearch, IPT/TIG domainsearch, Alpha amylase, C-terminal all-beta domainsearch

Chain ID Molecular function (GO) Biological process (GO)
A (P19531) carbohydrate bindingsearch starch bindingsearch catalytic activitysearch cation bindingsearch carbohydrate metabolic processsearch

Chain InterPro annotation
A Carbohydrate binding module family 20search IPT domainsearch Alpha amylasesearch Glycosyl hydrolase, family 13, catalytic domainsearch Alpha-amylase, C-terminal all betasearch Glycosyl hydrolase, family 13, subfamily, catalytic domainsearch Glycosyl hydrolase, family 13, all-betasearch Glycoside hydrolase, catalytic domainsearch Immunoglobulin-like foldsearch Carbohydrate-binding-like foldsearch Immunoglobulin E-setsearch Glycoside hydrolase, family 13search Glycoside hydrolase superfamilysearch