1qhg Summary

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STRUCTURE OF DNA HELICASE MUTANT WITH ADPNP

The structure was published by Soultanas, P., Dillingham, M.S., Velankar, S.S., and Wigley, D.B., in 1999 in a paper entitled "DNA binding mediates conformational changes and metal ion coordination in the active site of PcrA helicase." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.5 Å and deposited in 1999.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of ATP-DEPENDENT HELICASE PCRA. This molecule has the UniProt identifier P56255 (PCRA_GEOSE)search. The sample contained 724 residues which is 100% of the natural sequence. Out of 724 residues 621 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A ATP-DEPENDENT HELICASE PCRA P56255 (1-724) (PCRA_GEOSE)search Geobacillus stearothermophilussearch 100% 724 85%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P56255 (1 - 724) ATP-DEPENDENT HELICASE PCRA Geobacillus stearothermophilus

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P56255) Tandem AAA-ATPase domainsearch P-loop containing nucleotide triphosphate hydrolasessearch, Arc Repressor Mutant, subunit Asearch, PCRA; domain 4search PF00580: UvrD/REP helicase N-terminal domainsearch, PF13361: UvrD-like helicase C-terminal domainsearch

Chain ID Molecular function (GO) Cellular component (GO) Biological process (GO)
A (P56255) ATP bindingsearch ATP-dependent DNA helicase activitysearch hydrolase activitysearch DNA bindingsearch nucleotide bindingsearch helicase activitysearch cytoplasmsearch DNA unwinding involved in DNA replicationsearch

Chain InterPro annotation
A DNA helicase, UvrD/REP typesearch ATP-dependent DNA helicase PcrAsearch DExx box DNA helicase domainsearch UvrD-like Helicase, ATP-binding domainsearch DNA helicase, UvrD-like, C-terminalsearch P-loop containing nucleoside triphosphate hydrolasesearch