› 1qfg

X-ray diffraction
2.5Å resolution

E. COLI FERRIC HYDROXAMATE RECEPTOR (FHUA)

Released:
DOI: 10.2210/pdb1qfg/pdb
PDB entry 1qfg coloured by chain, front view.
PDB entry 1qfg coloured by chain, side view.
PDB entry 1qfg coloured by chain, top view.
Source organism: Escherichia coli
Primary publication:
A conserved structural motif for lipopolysaccharide recognition by procaryotic and eucaryotic proteins.
Ferguson AD, Welte W, Hofmann E, Lindner B, Holst O, Coulton JW, Diederichs K
Structure 8 585-92 (2000)
PMID: 10873859

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139315 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Ferrichrome outer membrane transporter/phage receptor Chain: A
Molecule details ›
Chain: A
Length: 725 amino acids
Theoretical weight: 80.05 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
  • Canonical: P06971 (Residues: 34-438, 439-747; Coverage: 100%)
Gene names: JW0146, b0150, fhuA, tonA
Sequence domains:
Structure domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: PA1, GCN, KDO, GMH, GLC, GLA
Carbohydrate polymer
8 bound ligands:
Ligand NI 1 x NI
Ligand PO4 2 x PO4
Ligand FTT 4 x FTT
Ligand DAO 1 x DAO
Ligand MYR 1 x MYR
Ligand DDQ 3 x DDQ
Ligand DPO 2 x DPO
Ligand GOL 8 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: MAX II BEAMLINE I711
Spacegroup: P61
Unit cell:
a: 171.55Å b: 171.55Å c: 87.65Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.221 0.221 0.271
Expression system: Escherichia coli

Quick links

Citations

26 review citations

Lipopolysaccharide endotoxins.
Raetz et al. (2002)
25 more

20 mentions without citation

Molecular basis of bacterial outer membrane permeability revisited.
Nikaido H. (2003)
19 more