1qdl Summary

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THE CRYSTAL STRUCTURE OF ANTHRANILATE SYNTHASE FROM SULFOLOBUS SOLFATARICUS

The structure was published by Knochel, T., Ivens, A., Hester, G., et al., Wilmanns, M., Kirschner, K., and Jansonius, J.N., in 1999 in a paper entitled "The crystal structure of anthranilate synthase from Sulfolobus solfataricus: functional implications." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.5 Å and deposited in 1999.

The experimental data on which the structure is based was also deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely PROTEIN (ANTHRANILATE SYNTHASE (TRPE-SUBUNIT)) and PROTEIN (ANTHRANILATE SYNTHASE (TRPG-SUBUNIT)).

The molecule most likely forms heterotetramers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A PROTEIN (ANTHRANILATE SYNTHASE (TRPE-SUBUNIT)) Q06128 (1-421) (TRPE_SULSO)search Sulfolobus solfataricus P2search 100% 422 98%
B PROTEIN (ANTHRANILATE SYNTHASE (TRPG-SUBUNIT)) Q06129 (1-195) (TRPG_SULSO)search Sulfolobus solfataricus P2search 100% 195 100%


This entry contains 2 unique UniProt proteins:

UniProt accession Name Organism PDB
Q06128 (1 - 421) PROTEIN (ANTHRANILATE SYNTHASE (TRPE-SUBUNIT)) Sulfolobus solfataricus
Q06129 (1 - 195) PROTEIN (ANTHRANILATE SYNTHASE (TRPG-SUBUNIT)) Sulfolobus solfataricus

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (Q06128) ADC synthasesearch Anthranilate synthasesearch PF00425: chorismate binding enzymesearch, PF04715: Anthranilate synthase component I, N terminal regionsearch
B (Q06129) Class I glutamine amidotransferases (GAT)search Rossmann foldsearch PF00117: Glutamine amidotransferase class-Isearch

Chain ID Biological process (GO) Molecular function (GO)
A (Q06128) tryptophan biosynthetic processsearch metabolic processsearch cellular amino acid biosynthetic processsearch biosynthetic processsearch aromatic amino acid family biosynthetic processsearch catalytic activitysearch anthranilate synthase activitysearch lyase activitysearch oxo-acid-lyase activitysearch metal ion bindingsearch
B (Q06129) tryptophan biosynthetic processsearch glutamine metabolic processsearch cellular amino acid biosynthetic processsearch aromatic amino acid family biosynthetic processsearch anthranilate synthase activitysearch lyase activitysearch

Chain InterPro annotation
A ADC synthasesearch Anthranilate synthase component I, N-terminalsearch Anthranilate synthase component I, archaeal typesearch Chorismate-utilising enzyme, C-terminalsearch Anthranilate synthase component I - likesearch
B Anthranilate synthase/para-aminobenzoate synthase like domainsearch Glutamine amidotransferasesearch Class I glutamine amidotransferase-likesearch