1qdl Summary



The structure was published by Knochel, T., Ivens, A., Hester, G., et al., Wilmanns, M., Kirschner, K., and Jansonius, J.N., in 1999 in a paper entitled "The crystal structure of anthranilate synthase from Sulfolobus solfataricus: functional implications." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.5 Å and deposited in 1999.

The experimental data on which the structure is based was also deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely PROTEIN (ANTHRANILATE SYNTHASE (TRPE-SUBUNIT)) and PROTEIN (ANTHRANILATE SYNTHASE (TRPG-SUBUNIT)).

The molecule most likely forms heterotetramers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A PROTEIN (ANTHRANILATE SYNTHASE (TRPE-SUBUNIT)) Q06128 (1-421) (TRPE_SULSO)search Sulfolobus solfataricus P2search 100% 422 98%
B PROTEIN (ANTHRANILATE SYNTHASE (TRPG-SUBUNIT)) Q06129 (1-195) (TRPG_SULSO)search Sulfolobus solfataricus P2search 100% 195 100%

This entry contains 2 unique UniProt proteins:

UniProt accession Name Organism PDB
Q06128 (1 - 421) PROTEIN (ANTHRANILATE SYNTHASE (TRPE-SUBUNIT)) Sulfolobus solfataricus
Q06129 (1 - 195) PROTEIN (ANTHRANILATE SYNTHASE (TRPG-SUBUNIT)) Sulfolobus solfataricus

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (Q06128) ADC synthasesearch Anthranilate synthasesearch PF00425: chorismate binding enzymesearch, PF04715: Anthranilate synthase component I, N terminal regionsearch
B (Q06129) Class I glutamine amidotransferases (GAT)search Rossmann foldsearch PF00117: Glutamine amidotransferase class-Isearch

Chain ID Molecular function (GO) Biological process (GO)
A (Q06128) oxo-acid-lyase activitysearch lyase activitysearch metal ion bindingsearch catalytic activitysearch anthranilate synthase activitysearch tryptophan biosynthetic processsearch aromatic amino acid family biosynthetic processsearch cellular amino acid biosynthetic processsearch metabolic processsearch biosynthetic processsearch
B (Q06129) anthranilate synthase activitysearch lyase activitysearch aromatic amino acid family biosynthetic processsearch glutamine metabolic processsearch cellular amino acid biosynthetic processsearch tryptophan biosynthetic processsearch metabolic processsearch

Chain InterPro annotation
A ADC synthasesearch Anthranilate synthase component I, N-terminalsearch Anthranilate synthase component I, archaeal typesearch Chorismate-utilising enzyme, C-terminalsearch Anthranilate synthase component I - likesearch
B Anthranilate synthase/para-aminobenzoate synthase like domainsearch Glutamine amidotransferasesearch Class I glutamine amidotransferase-likesearch