› 1qbp

X-ray diffraction
2.1Å resolution

CRYSTAL STRUCTURE OF A BROMINATED RNA HELIX WITH FOUR MISMATCHED BASE PAIRS

Released:
DOI: 10.2210/pdb1qbp/pdb
PDB entry 1qbp coloured by chain, front view.
PDB entry 1qbp coloured by chain, side view.
PDB entry 1qbp coloured by chain, top view.
Source organism: Synthetic construct
Primary publication:
Crystal structure of a brominated RNA helix with four mismatched base pairs: An investigation into RNA conformational variability.
Anderson AC, O'Neil RH, Filman DJ, Frederick CA
Biochemistry 38 12577-85 (1999)
PMID: 10504226

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-196172 (preferred)
Entry contents:
1 distinct RNA molecule
Macromolecule:
5'-R(*UP*GP*(CBV)P*(CBV)P*AP*GP*UP*UP*CP*GP*CP*UP*GP*GP*C)-3' Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 15 nucleotides
Theoretical weight: 4.92 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
1 modified residue:
Ligand CBV 12 x CBV

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL1-5
Spacegroup: C2
Unit cell:
a: 104.45Å b: 24.27Å c: 104.45Å
α: 90° β: 118.76° γ: 90°
R-values:
R R work R free
0.217 0.217 0.253
Expression system: Not provided

Quick links

Citations

1 review citation

Challenges with osmolytes as inhibitors of protein aggregation: Can nucleic acid aptamers provide an answer?
Patel et al. (2017)
5 other articles

1 mention without citation

An atlas of RNA base pairs involving modified nucleobases with optimal geometries and accurate energies.
Chawla et al. (2015)