1q6l Summary

pdbe.org/1q6l
spacer

Structure of 3-keto-L-gulonate 6-phosphate decarboxylase with bound L-threonohydroxamate 4-phosphate

The structure was published by Wise, E.L., Yew, W.S., Gerlt, J.A., and Rayment, I., in 2003 in a paper entitled "Structural Evidence for a 1,2-Enediolate Intermediate in the Reaction Catalyzed by 3-Keto-l-Gulonate 6-Phosphate Decarboxylase, a Member of the Orotidine 5'-Monophosphate Decarboxylase Suprafamily" (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 1.8 Å and deposited in 2003.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of 3-keto-L-gulonate 6-phosphate decarboxylase.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A 3-keto-L-gulonate 6-phosphate decarboxylase P39304 (1-216) (ULAD_ECOLI)search Escherichia coli K-12search 100% 216 99%
B 3-keto-L-gulonate 6-phosphate decarboxylase P39304 (1-216) (ULAD_ECOLI)search Escherichia coli K-12search 100% 216 99%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P39304 (1 - 216) 3-keto-L-gulonate 6-phosphate decarboxylase Escherichia coli

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B (P39304) Decarboxylasesearch Aldolase class Isearch PF00215: Orotidine 5'-phosphate decarboxylase / HUMPS familysearch

Chain ID Biological process (GO) Molecular function (GO)
A, B (P39304) metabolic processsearch L-ascorbic acid catabolic processsearch 'de novo' pyrimidine nucleobase biosynthetic processsearch carbohydrate metabolic processsearch orotidine-5'-phosphate decarboxylase activitysearch catalytic activitysearch magnesium ion bindingsearch 3-dehydro-L-gulonate-6-phosphate decarboxylase activitysearch lyase activitysearch metal ion bindingsearch carboxy-lyase activitysearch

Chain InterPro annotation
A, B Orotidine 5'-phosphate decarboxylase domainsearch Ribulose-phosphate binding barrelsearch Aldolase-type TIM barrelsearch 3-keto-L-gulonate-6-phosphate decarboxylase, UlaDsearch