Crystal Structure of Human Thyroid Hormone Receptor beta LBD in complex with specific agonist GC-24
The structure was published by Borngraeber, S., Budny, M.J., Chiellini, G., et al., Baxter, J.D., Scanlan, T.S., and Fletterick, R.J., in 2003 in a paper entitled "Ligand selectivity by seeking hydrophobicity in thyroid hormone receptor." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.8 Å and deposited in 2003.
The experimental data on which the structure is based was also deposited.
The PDB entry contains the structure of Thyroid hormone receptor beta-1. This molecule has the UniProt identifier P10828 (THB_HUMAN). The sample contained 253 residues which is < 90% of the natural sequence. Out of 253 residues 237 were observed and are deposited in the PDB.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule is most likely monomeric.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: