1q18 Summary


Crystal structure of E.coli glucokinase (Glk)

The structure was published by Lunin, V.V., Li, Y., Schrag, J.D., Iannuzzi, P., Cygler, M., and Matte, A., in 2004 in a paper entitled "Crystal structures of Escherichia coli ATP-dependent glucokinase and its complex with glucose." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.36 Å and deposited in 2003.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of Glucokinase.

The molecule most likely forms homodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Glucokinase P0A6V9 (2-321) (GLK_ECO57)search Escherichia coli O157:H7search 100% 332 96%
B Glucokinase P0A6V9 (2-321) (GLK_ECO57)search Escherichia coli O157:H7search 100% 332 96%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P0A6V9 (2 - 321) Glucokinase Escherichia coli

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B (P0A6V9) Glucokinasesearch Nucleotidyltransferase; domain 5search, Hexokinase; domain 1search PF02685: Glucokinasesearch

Chain ID Cellular component (GO) Biological process (GO) Molecular function (GO)
A, B (P0A6V9) cytoplasmsearch glycolytic processsearch glucose 6-phosphate metabolic processsearch phosphorylationsearch nucleotide bindingsearch glucokinase activitysearch ATP bindingsearch transferase activitysearch kinase activitysearch

Chain InterPro annotation
A, B Glucokinasesearch