CRYSTAL STRUCTURE OF DICLOFENAC BOUND TO THE CYCLOOXYGENASE ACTIVE SITE OF COX-2
The structure was published by Rowlinson, S.W., Kiefer, J.R., Prusakiewicz, J.J., et al., Stallings, W.C., Kurumbail, R.G., and Marnett, L.J., in 2003 in a paper entitled "A Novel Mechanism of Cyclooxygenase-2 Inhibition Involving Interactions with Ser-530 and Tyr-385." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.9 Å and deposited in 2003.
The experimental data on which the structure is based was also deposited.
This PDB entry contains multiple copies of the structure of Prostaglandin G/H synthase 2.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: