1pvl Summary

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STRUCTURE OF THE PANTON-VALENTINE LEUCOCIDIN F COMPONENT FROM STAPHYLOCOCCUS AUREUS

There is a Quite Interesting Protein Structure article for this entry.

The structure was published by Pedelacq, J.D., Maveyraud, L., Prevost, G., et al., Monteil, H., Samama, J.P., and Mourey, L., in 1999 in a paper entitled "The structure of a Staphylococcus aureus leucocidin component (LukF-PV) reveals the fold of the water-soluble species of a family of transmembrane pore-forming toxins." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.0 Å and deposited in 1999.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of LEUCOCIDIN. This molecule has the UniProt identifier Q5FBD2 (Q5FBD2_STAAU)search. The sample contained 301 residues which is 93% of the natural sequence. Out of 301 residues 296 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A LEUCOCIDIN Q5FBD2 (25-325) (Q5FBD2_STAAU)search Staphylococcus aureussearch 93% 301 99%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q5FBD2 (25 - 325) LEUCOCIDIN Staphylococcus aureus

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A Leukocidin (pore-forming toxin)search Leukocidin-likesearch Leukocidin/Hemolysin toxin familysearch

Chain ID Cellular component (GO) Biological process (GO)
A (Q5FBD2) extracellular regionsearch pathogenesissearch cytolysis in other organismsearch

Chain InterPro annotation
A Bi-component toxin, staphylococcisearch Leukocidin/porinsearch