1ppd Summary



The structure was published by Priestle, J.P., Ford, G.C., Glor, M., et al., Smit, J.D.G., Thaller, C., and Jansonius, J.N., in 1984 in a paper entitled "Restrained Least-Squares Refinement of the Sulfhydryl Protease Papain to 2.0 Angstroms" (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.0 Å and deposited in 1984.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of 2-HYDROXYETHYL-THIOPAPAIN. This molecule has the UniProt identifier P00784 (PAPA1_CARPA)search. The sample contained 212 residues which is < 90% of the natural sequence. Out of 212 residues 212 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A 2-HYDROXYETHYL-THIOPAPAIN P00784 (134-345) (PAPA1_CARPA)search Carica papayasearch 98% 212 100%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P00784 (134 - 345) 2-HYDROXYETHYL-THIOPAPAIN Carica papaya

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P00784) Papain-likesearch Cysteine proteinasessearch PF00112: Papain family cysteine proteasesearch

Chain ID Molecular function (GO) Biological process (GO)
A (P00784) cysteine-type peptidase activitysearch proteolysissearch

Chain InterPro annotation
A Cysteine peptidase, cysteine active sitesearch Peptidase C1A, papain C-terminalsearch Peptidase C1Asearch Cysteine peptidase, histidine active sitesearch Cysteine peptidase, asparagine active sitesearch