1pmx Summary

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INSULIN-LIKE GROWTH FACTOR-I BOUND TO A PHAGE-DERIVED PEPTIDE

The structure was published by Schaffer, M.L., Deshayes, K., Nakamura, G., Sidhu, S., and Skelton, N.J., in 2003 in a paper entitled "Complex with a Phage Display-Derived Peptide Provides Insight into the Function of Insulin-like Growth Factor I" (abstract).

The structure was determined using NMR spectroscopy and deposited in 2003.

The experimental data on which the structure is based was not deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely Insulin-like growth factor IB and IGF-1 ANTAGONIST F1-1.

The molecule most likely forms heterodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Insulin-like growth factor IB P05019 (49-118) (IGF1_HUMAN)search Homo sapienssearch < 90% 70 100%
B IGF-1 ANTAGONIST F1-1 Not available
Synthetic Not available 16 100%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P05019 (49 - 118) Insulin-like growth factor IB Homo sapiens

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A Insulin-likesearch Insulin-like, subunit Esearch Insulin/IGF/Relaxin familysearch
B

Chain ID Molecular function (GO) Cellular component (GO)
A (P05019) growth factor activitysearch hormone activitysearch extracellular regionsearch extracellular spacesearch

Chain InterPro annotation
A Insulin-likesearch Insulin-like growth factor Isearch Insulin-like growth factorsearch Insulin familysearch Insulin, conserved sitesearch
B