The structure of JNK3 in complex with an imidazole-pyrimidine inhibitor
The structure was published by Scapin, G., Patel, S.B., Lisnock, J., Becker, J.W., and LoGrasso, P.V., in 2003 in a paper entitled "The structure of JNK3 in complex with small molecule inhibitors: structural basis for potency and selectivity" (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.2 Å and deposited in 2003.
The experimental data on which the structure is based was also deposited.
The PDB entry contains the structure of Mitogen-activated protein kinase 10. This molecule has the UniProt identifier P53779 (MK10_HUMAN). The sample contained 364 residues which is < 90% of the natural sequence. Out of 364 residues 345 were observed and are deposited in the PDB.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule is most likely monomeric.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: