1pmi Summary


Candida Albicans Phosphomannose Isomerase

The structure was published by Cleasby, A., Wonacott, A., Skarzynski, T., et al., Bernard, A.R., Payton, M.A., and Wells, T.N., in 1996 in a paper entitled "The x-ray crystal structure of phosphomannose isomerase from Candida albicans at 1.7 angstrom resolution." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 1.7 Å and deposited in 1996.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of PHOSPHOMANNOSE ISOMERASE. This molecule has the UniProt identifier P34948 (MPI_CANAL)search. The sample contained 440 residues which is 100% of the natural sequence. Out of 440 residues 439 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A PHOSPHOMANNOSE ISOMERASE P34948 (2-441) (MPI_CANAL)search Candida albicans SC5314search 100% 440 100%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P34948 (2 - 441) PHOSPHOMANNOSE ISOMERASE Candida albicans

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P34948) Type I phosphomannose isomerasesearch Jelly Rollssearch, Phosphomannose Isomerase, domain 2search PF01238: Phosphomannose isomerase type Isearch

Chain ID Molecular function (GO) Cellular component (GO) Biological process (GO)
A (P34948) zinc ion bindingsearch mannose-6-phosphate isomerase activitysearch isomerase activitysearch metal ion bindingsearch cytoplasmsearch GDP-mannose biosynthetic processsearch carbohydrate metabolic processsearch fungal-type cell wall organizationsearch

Chain InterPro annotation
A Mannose-6-phosphate isomerase, type Isearch RmlC-like cupin domainsearch RmlC-like jelly roll foldsearch Mannose-6-phosphate isomerasesearch Phosphomannose isomerase, type I, conserved sitesearch