STRUCTURE OF PENTA MUTANT HUMAN ERK2 MAP KINASE COMPLEXED WITH A SPECIFIC INHIBITOR OF HUMAN P38 MAP KINASE
The structure was published by Fox, T., Coll, J.T., Xie, X., et al., Galullo, V., Su, M.S., and Wilson, K.P., in 1998 in a paper entitled "A single amino acid substitution makes ERK2 susceptible to pyridinyl imidazole inhibitors of p38 MAP kinase." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.0 Å and deposited in 1998.
The experimental data on which the structure is based was not deposited.
The PDB entry contains the structure of ERK2. This molecule has the UniProt identifier P28482 (MK01_HUMAN). The sample contained 380 residues which is 100% of the natural sequence. Out of 380 residues 333 were observed and are deposited in the PDB.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule is most likely monomeric.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: