1pf9 Summary

pdbe.org/1pf9
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GroEL-GroES-ADP

The structure was published by Chaudhry, C., Farr, G.W., Todd, M.J., et al., Adams, P.D., Horwich, A.L., and Sigler, P.B., in 2003 in a paper entitled "Role of the gamma-phosphate of ATP in triggering protein folding by GroEL-GroES: function, structure and energetics." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.993 Å and deposited in 2003.

The experimental data on which the structure is based was also deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely groEL protein and groES protein.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The most likely quaternary structure is a 21meric assembly.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A groEL protein P0A6F5 (2-525) (CH60_ECOLI)search Escherichia coli K-12search 96% 524 100%
B groEL protein P0A6F5 (2-525) (CH60_ECOLI)search Escherichia coli K-12search 96% 524 100%
C groEL protein P0A6F5 (2-525) (CH60_ECOLI)search Escherichia coli K-12search 96% 524 100%
D groEL protein P0A6F5 (2-525) (CH60_ECOLI)search Escherichia coli K-12search 96% 524 100%
E groEL protein P0A6F5 (2-525) (CH60_ECOLI)search Escherichia coli K-12search 96% 524 100%
F groEL protein P0A6F5 (2-525) (CH60_ECOLI)search Escherichia coli K-12search 96% 524 100%
G groEL protein P0A6F5 (2-525) (CH60_ECOLI)search Escherichia coli K-12search 96% 524 100%
H groEL protein P0A6F5 (2-525) (CH60_ECOLI)search Escherichia coli K-12search 96% 524 100%
I groEL protein P0A6F5 (2-525) (CH60_ECOLI)search Escherichia coli K-12search 96% 524 100%
J groEL protein P0A6F5 (2-525) (CH60_ECOLI)search Escherichia coli K-12search 96% 524 100%
K groEL protein P0A6F5 (2-525) (CH60_ECOLI)search Escherichia coli K-12search 96% 524 100%
L groEL protein P0A6F5 (2-525) (CH60_ECOLI)search Escherichia coli K-12search 96% 524 100%
M groEL protein P0A6F5 (2-525) (CH60_ECOLI)search Escherichia coli K-12search 96% 524 100%
N groEL protein P0A6F5 (2-525) (CH60_ECOLI)search Escherichia coli K-12search 96% 524 100%
O groES protein P0A6F9 (1-97) (CH10_ECOLI)search Escherichia coli K-12search 100% 97 100%
P groES protein P0A6F9 (1-97) (CH10_ECOLI)search Escherichia coli K-12search 100% 97 100%
Q groES protein P0A6F9 (1-97) (CH10_ECOLI)search Escherichia coli K-12search 100% 97 100%
R groES protein P0A6F9 (1-97) (CH10_ECOLI)search Escherichia coli K-12search 100% 97 100%
S groES protein P0A6F9 (1-97) (CH10_ECOLI)search Escherichia coli K-12search 100% 97 100%
T groES protein P0A6F9 (1-97) (CH10_ECOLI)search Escherichia coli K-12search 100% 97 100%
U groES protein P0A6F9 (1-97) (CH10_ECOLI)search Escherichia coli K-12search 100% 97 100%


This entry contains 2 unique UniProt proteins:

UniProt accession Name Organism PDB
P0A6F5 (2 - 525) groEL protein Escherichia coli
P0A6F9 (1 - 97) groES protein Escherichia coli

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B, C, D, E, F, G, H, I, J, K, L, M, N (P0A6F5) GroEL chaperone, ATPase domainsearch, GroEL-like chaperone, apical domainsearch, GroEL-like chaperone, intermediate domainsearch GROEL, domain 1search, GROEL, domain 2search, GroELsearch PF00118: TCP-1/cpn60 chaperonin familysearch
O, P, Q, R, S, T, U (P0A6F9) GroESsearch 10 Kd Chaperonin, Protein Cpn10; Chain Osearch PF00166: Chaperonin 10 Kd subunitsearch

Chain ID Molecular function (GO) Cellular component (GO) Biological process (GO)
A, B, C, D, E, F, G, H, I, J, K, L, M, N (P0A6F5) ATP bindingsearch identical protein bindingsearch protein bindingsearch unfolded protein bindingsearch ATPase activitysearch nucleotide bindingsearch cytosolsearch cytoplasmsearch membranesearch protein refoldingsearch protein foldingsearch cellular protein metabolic processsearch ATP catabolic processsearch cell cyclesearch virion assemblysearch response to heatsearch cell divisionsearch
O, P, Q, R, S, T, U (P0A6F9) ATP bindingsearch unfolded protein bindingsearch protein bindingsearch identical protein bindingsearch cytoplasmsearch cytosolsearch protein foldingsearch cell divisionsearch virion assemblysearch cell cyclesearch response to heatsearch

Chain InterPro annotation
A, B, C, D, E, F, G, H, I, J, K, L, M, N Chaperonin Cpn60search Chaperonin Cpn60/TCP-1search Chaperonin Cpn60, conserved sitesearch GroEL-like apical domainsearch GroEL-like equatorial domainsearch
O, P, Q, R, S, T, U GroES (chaperonin 10)-likesearch Chaperonin Cpn10, conserved sitesearch Chaperonin Cpn10search