1pa3 Summary


Crystal Structure of Glutathione-S-transferase from Plasmodium falciparum

The structure was published by Perbandt, M., Burmeister, C., Walter, R.D., Betzel, C., and Liebau, E., in 2004 in a paper entitled "Native and inhibited structure of a Mu class-related glutathione S-transferase from Plasmodium falciparum" (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.7 Å and deposited in 2003.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of Glutathione s-transferase, putative.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Glutathione s-transferase, putative Q8MU52 (1-211) (GST_PLAFA)search Plasmodium falciparumsearch 100% 211 92%
B Glutathione s-transferase, putative Q8MU52 (1-211) (GST_PLAFA)search Plasmodium falciparumsearch 100% 211 92%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q8MU52 (1 - 211) Glutathione s-transferase, putative Plasmodium falciparum

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B (Q8MU52) Glutathione S-transferase (GST), C-terminal domainsearch, Glutathione S-transferase (GST), N-terminal domainsearch Glutaredoxinsearch, Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2search PF02798: Glutathione S-transferase, N-terminal domainsearch, PF14497: Glutathione S-transferase, C-terminal domainsearch

Chain ID Molecular function (GO) Biological process (GO)
A, B (Q8MU52) transferase activitysearch glutathione transferase activitysearch metabolic processsearch

Chain InterPro annotation
A, B Glutathione S-transferase, N-terminalsearch Glutathione S-transferase, C-terminalsearch Glutathione S-transferase, C-terminal-likesearch Thioredoxin-like foldsearch