1p7m Summary

pdbe.org/1p7m
spacer

SOLUTION STRUCTURE AND BASE PERTURBATION STUDIES REVEAL A NOVEL MODE OF ALKYLATED BASE RECOGNITION BY 3-METHYLADENINE DNA GLYCOSYLASE I

The structure was published by Cao, C., Kwon, K., Jiang, Y.L., Drohat, A.C., and Stivers, J.T., in 2003 in a paper entitled "Solution structure and base perturbation studies reveal a novel mode of alkylated base recognition by 3-methyladenine DNA glycosylase I" (abstract).

The structure was determined using NMR spectroscopy and deposited in 2003.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of DNA-3-methyladenine glycosylase I. This molecule has the UniProt identifier P05100 (3MG1_ECOLI)search. The sample contained 187 residues which is 100% of the natural sequence. Out of 187 residues 187 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A DNA-3-methyladenine glycosylase I P05100 (1-187) (3MG1_ECOLI)search Escherichia coli K-12search 100% 187 100%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P05100 (1 - 187) DNA-3-methyladenine glycosylase I Escherichia coli

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P05100) 3-Methyladenine DNA glycosylase I (Tag)search Hypothetical protein; domain 2search PF03352: Methyladenine glycosylasesearch

Chain ID Molecular function (GO) Biological process (GO)
A (P05100) DNA-3-methyladenine glycosylase activitysearch catalytic activitysearch hydrolase activitysearch metal ion bindingsearch base-excision repairsearch DNA repairsearch cellular response to DNA damage stimulussearch DNA dealkylation involved in DNA repairsearch

Chain InterPro annotation
A DNA-3-methyladenine glycosylase Isearch Methyladenine glycosylasesearch DNA glycosylasesearch