DEATH ASSOCIATED PROTEIN KINASE CATALYTIC DOMAIN WITH BOUND INHIBITOR FRAGMENT
The structure was published by Velentza, A.V., Wainwright, M.S., Zasadzki, M., et al., Focia, P.J., Egli, M., and Watterson, D.M., in 2003 in a paper entitled "An aminopyridazine-based inhibitor of a pro-apoptotic protein kinase attenuates hypoxia-ischemia induced acute brain injury." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 1.9 Å and deposited in 2003.
The experimental data on which the structure is based was also deposited.
The PDB entry contains the structure of Death-associated protein kinase 1. This molecule has the UniProt identifier P53355 (DAPK1_HUMAN). The sample contained 293 residues which is < 90% of the natural sequence. Out of 293 residues 269 were observed and are deposited in the PDB.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule is most likely monomeric.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: