› 1p35

X-ray diffraction
2.2Å resolution

CRYSTAL STRUCTURE OF BACULOVIRUS P35

Released:
DOI: 10.2210/pdb1p35/pdb
PDB entry 1p35 coloured by chain, front view.
PDB entry 1p35 coloured by chain, side view.
PDB entry 1p35 coloured by chain, top view.
Source organism: Autographa californica nucleopolyhedrovirus
Primary publication:
Crystal structure of baculovirus P35: role of a novel reactive site loop in apoptotic caspase inhibition.
Fisher AJ, Cruz Wd, Zoog SJ, Schneider CL, Friesen PD
EMBO J 18 2031-9 (1999)
PMID: 10205157

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139943 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Early 35 kDa protein Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 299 amino acids
Theoretical weight: 34.81 KDa
Source organism: Autographa californica nucleopolyhedrovirus
Expression system: Escherichia coli
UniProt:
  • Canonical: P08160 (Residues: 2-299; Coverage: 100%)
Gene name: P35
Sequence domains: Apoptosis preventing protein
Structure domains: Baculovirus p35

Ligands and Environments

2 bound ligands:
Ligand PO4 3 x PO4
Ligand EDO 3 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL7-1
Spacegroup: C2221
Unit cell:
a: 114.58Å b: 130.11Å c: 181.08Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.196 0.196 0.262
Expression system: Escherichia coli

Quick links

Citations

19 review citations

Triggering and modulation of apoptosis by oxidative stress.
Chandra et al. (2000)
18 more

110 mentions without citation

The SLC2 (GLUT) family of membrane transporters.
Mueckler et al. (2013)
109 more