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PDBe Entry: 1p22
Structure of a beta-TrCP1-Skp1-beta-catenin complex: destruction motif binding and lysine specificity on the SCFbeta-TrCP1 ubiquitin ligase
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| Summary | ![]() |
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| Header |
SIGNALING PROTEIN
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| Method | X-RAY DIFFRACTION | |||||||||||||||||||||||||
| Experiment | Resolution: 2.95 Å, R-factor: 23.315%, Free R-factor: 28.554%, Spacegroup: P 31 | |||||||||||||||||||||||||
| Released | 08/07/2003, deposition: 14/04/2003, last revision: 24/02/2009 | |||||||||||||||||||||||||
| Authors |
Wu, G. ; Xu, G. ; Schulman, B.A. ; Jeffrey, P.D. ; Harper, J.W. ; Pavletich, N.P.
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| Primary citation |
Structure of a beta-TrCP1-Skp1-beta-Catenin complex: destruction motif binding and lysine specificity of the SCFbeta-TrCP1 ubiquitin ligase MOL.CELL vol:11, pag:1445-1456 (2003) [PubMed ID 12820959 ]
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| Keywords |
Ubiquitination , degradation , SIGNALING PROTEIN
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| Organism |
Homo sapiens(human) 9606 (A B C)
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| UniProt |
F-box/WD repeat-containing protein 1A (F-box and WD repeats protein beta-TrCP) (E3RSIkappaB) (pIkappaBalpha-E3 receptor subunit) Q9Y297 (A)S-phase kinase-associated protein 1 (Cyclin A/CDK2-associated protein p19) (p19skp1) (p19A) (RNA polymerase II elongation factor-like protein) (Organ of Corti protein 2) (OCP-2) (OCP-II) (Transcription elongation factor B) (SIII) P63208 (B)Catenin beta-1 (Beta-catenin) P35222 (C)
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| Polymers |
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