 |
PDBe Entry: 1p0p 
Crystal structure of soman-aged human butyryl cholinesterase in complex with the substrate analog butyrylthiocholine
 |
HYDROLASE
|
|
X-RAY DIFFRACTION
|
|
Resolution: 2.3 Å, R-factor: 19.9%, Free R-factor: 24.2%, Spacegroup: I 4 2 2
|
|
05/08/2003, deposition: 10/04/2003, last revision: 24/02/2009
|
|
Nicolet, Y.; Lockridge, O.; Masson, P.; Fontecilla-Camps, J.C.; Nachon, F.
|
Crystal structure of human butyrylcholinesterase and of its complexes with substrate and products.
J.BIOL.CHEM. vol:278, pag:41141-41147 (2003) [PubMed ID 12869558 ]
|
|
Serine hydrolase, organophosphates, soman, butyrylthiocholine, cholinesterase
|
|
3.1.1.8 ExPASy BRENDA (A)
|
|
Homo sapiens(human) 9606(A)
|
|
Cholinesterase precursor (EC 3.1.1.8) (Acylcholine acylhydrolase) (Choline esterase II) (Butyrylcholine esterase) (Pseudocholinesterase) P06276 (A)
|
|
A
|
|
1p0i, 1p0m, 1p0q
|
| A |
Cholinesterase |
Protein |
P06276 (CHLE_HUMAN)
|
529 |
98% |
|
| A |
SUGAR (3-MER) |
NAG
FUC
|
| A |
SUGAR (N-ACETYL-D-GLUCOSAMINE) |
NAG
|
| A |
SULFATE ION |
SO4
|
| A |
CHLORIDE ION |
CL
|
| A |
METHYLPHOSPHONIC ACID ESTER GROUP |
VXA
|
| A |
2-(BUTYRYLSULFANYL)-N,N,N-TRIMETHYLETHANAMINIUM |
BCH
|
| A |
GLYCEROL |
GOL
|
|
|
