1ozo Summary

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Three-dimensional solution structure of apo-S100P protein determined by NMR spectroscopy

The structure was published by Lee, Y.-C., Volk, D.E., Thiviyanathan, V., et al., Gorenstein, D.G., Makhatadze, G.I., and Luxon, B.A., in 2004 in a paper entitled "NMR structure of the Apo-S100P protein." (abstract).

The structure was determined using NMR spectroscopy and deposited in 2003.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of S-100P protein.

The molecule most likely forms homodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A S-100P protein P25815 (1-95) (S100P_HUMAN)search Homo sapienssearch 100% 95 100%
B S-100P protein P25815 (1-95) (S100P_HUMAN)search Homo sapienssearch 100% 95 100%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P25815 (1 - 95) S-100P protein Homo sapiens

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B (P25815) S100 proteinssearch EF-handsearch PF01023: S-100/ICaBP type calcium binding domainsearch

Chain ID Molecular function (GO) Cellular component (GO) Biological process (GO)
A, B (P25815) magnesium ion bindingsearch calcium-dependent protein bindingsearch protein bindingsearch calcium ion bindingsearch metal ion bindingsearch RAGE receptor bindingsearch membranesearch nucleussearch cell projectionsearch extracellular vesicular exosomesearch cytoplasmsearch plasma membranesearch response to organic substancesearch endothelial cell migrationsearch

Chain InterPro annotation
A, B S100/Calbindin-D9k, conserved sitesearch EF-hand domainsearch EF-hand domain pairsearch S100/CaBP-9k-type, calcium binding, subdomainsearch Protein S100-Psearch