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EBI PDBe PDBeView

PDBe Entry: 1omz view

crystal structure of mouse alpha-1,4-N-acetylhexosaminyltransferase (EXTL2) in complex with UDPGalNAc
Summary
Header TRANSFERASEsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 2.1 Å, R-factor: 20.3%, Free R-factor: 23.3%, Spacegroup: P 4 21 2
Released 22/04/2003, deposition: 26/02/2003, last revision: 24/02/2009
Authors Pedersen, L.C.search; Dong, J.search; Taniguchi, F.search; Kitagawa, H.search; Krahn, J.M.search; Pedersen, L.G.search; Sugahara, K.search; Negishi, M.search
Primary citation Crystal structure of an alpha-1,4-N-acetylhexosaminyltransferase (EXTL2), a member of the exostosin gene family involved in heparan sulfate biosynthesis
J.BIOL.CHEM.search vol:278, pag:14420-14428 (2003) [PubMed ID 12562774 ]search
Keywords Rossmann foldsearch, DXD motifsearch, TRANSFERASEsearch
EC 2.4.1.223 ExPASy BRENDA search (A B)
Organism Mus musculus(house mouse) 10090search(A B)
UniProt Exostosin-like 2 (EC 2.4.1.223) (Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Alpha-1,4-N-acetylhexosaminyltransferase EXTL2) (Alpha-GalNAcT EXTL2) (EXT-related protein 2) Q9ES89search (A B)
Solvent A, B
Related entries 1omx, 1on6, 1on8
Polymers
Id Name Type UniProt Residues Observed
A, B Alpha-1,4-N-acetylhexosaminyltransferase EXTL2 Protein Q9ES89 (EXTL2_MOUSE)search
 293 87%
Heterogens
Id Name Ligands
A, B MANGANESE (II) ION MN search
B, A URIDINE-DIPHOSPHATE-N-ACETYLGALACTOSAMINE UD2 search
A, B 1,2-ETHANEDIOL EDO search
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