Crystal Structure of the complex between G Protein-Coupled Receptor Kinase 2 and Heterotrimeric G Protein beta 1 and gamma 2 subunits
The structure was published by Lodowski, D.T., Pitcher, J.A., Capel, W.D., Lefkowitz, R.J., and Tesmer, J.J.G., in 2003 in a paper entitled "Keeping G proteins at Bay: A Complex Between G Protein-Coupled Receptor Kinase 2 and G-Beta-Gamma" (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.5 Å and deposited in 2003.
The experimental data on which the structure is based was also deposited.
This PDB entry contains a complex of 3 biomacromolecules, namely G-protein coupled receptor kinase 2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) beta subunit 1, and Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunit.
The molecule most likely forms heterotrimers.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 3 unique UniProt proteins: