1om1 Summary

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Crystal structure of maize CK2 alpha in complex with IQA

The structure was published by Sarno, S., de Moliner, E., Ruzzene, M., et al., Meggio, F., Zanotti, G., and Pinna, L.A., in 2003 in a paper entitled "Biochemical and three-dimensional-structural study of the specific inhibition of protein kinase CK2 by [5-oxo-5,6-dihydroindolo-(1,2-a)quinazolin-7-yl]acetic acid (IQA)." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 1.68 Å and deposited in 2003.

The experimental data on which the structure is based was not deposited.

The PDB entry contains the structure of Casein kinase II, alpha chain. This molecule has the UniProt identifier P28523 (CSK2A_MAIZE)search. The sample contained 332 residues which is 100% of the natural sequence. Out of 332 residues 325 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Casein kinase II, alpha chain P28523 (1-332) (CSK2A_MAIZE)search Zea mayssearch 98% 332 97%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P28523 (1 - 332) Casein kinase II, alpha chain Zea mays

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P28523) Protein kinases, catalytic subunitsearch Phosphorylase Kinase; domain 1search, Transferase(Phosphotransferase) domain 1search PF00069: Protein kinase domainsearch

Chain ID Biological process (GO) Molecular function (GO)
A (P28523) protein phosphorylationsearch phosphorylationsearch protein kinase activitysearch ATP bindingsearch transferase activity, transferring phosphorus-containing groupssearch protein serine/threonine kinase activitysearch transferase activitysearch nucleotide bindingsearch kinase activitysearch

Chain InterPro annotation
A Protein kinase domainsearch Serine/threonine/dual specificity protein kinase, catalytic domainsearch Serine/threonine-protein kinase, active sitesearch Protein kinase-like domainsearch Protein kinase, ATP binding sitesearch