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EBI PDBe PDBeView

PDBe Entry: 1o7q view

ROLES OF INDIVIDUAL RESIDUES OF ALPHA-1,3 GALACTOSYLTRANSFERASES IN SUBSTRATE BINDING AND CATALYSIS
Summary
Header TRANSFERASEsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 1.3 Å, R-factor: 11.55%, Free R-factor: 15.43%, Spacegroup: P 1 21 1
Released 06/11/2003, deposition: 12/11/2002, last revision: 24/02/2009
Authors Zhang, Y.search; Swaminathan, G.J.search; Deshpande, A.search; Natesh, R.search; Xie, X.search; Acharya, K.R.search; Brew, K.search
Primary citation Roles of Individual Enzyme-Substrate Interactions by Alpha-1,3-Galactosyltransferase in Catalysis and Specificity.
BIOCHEMISTRYsearch vol:42, pag:13512 (2003) [PubMed ID 14621997 ]search
Keywords TRANSFERASEsearch, ALPHA-1search, 3-GALACTOSYLTRANSFERASE-UDP COMPLEXsearch, GLYCOSYLTRANSFERASEsearch, GLYCOPROTEINsearch, TRANSMEMBRANEsearch, NUCLEOTIDE-BINDING PROTEINsearch, XENOTRANSPLANTATIONsearch
EC 2.4.1.87 ExPASy BRENDA search (A B)
Organism Bos taurus(cattle) 9913search(A B)
UniProt N-acetyllactosaminide alpha-1,3-galactosyltransferase (EC 2.4.1.87) (UDP-galactose:beta-D-galactosyl-1,4-N-acetyl-D-glucosaminide alpha-1,3-galactosyltransferase) (Galactosyltransferase) P14769search (A B)
Solvent A, B
Related entries 1fg5, 1g8o, 1g93, 1gwv, 1gww, 1gx0, 1gx4, 1k4v, 1o7o, 1o7r
Polymers
Id Name Type UniProt Residues Observed
A, B N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE Protein P14769 (GGTA1_BOVIN)search
 289 99%
Heterogens
Id Name Ligands
A, B GLYCEROL GOL search
A, B MANGANESE (II) ION MN search
A, B SUGAR (2-MER) GAL search NAG search
A, B URIDINE-5'-DIPHOSPHATE UDP search
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