1o1p Summary

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Deoxy hemoglobin (A-GLY-C:V1M; B,D:V1M,C93A,N108K)

The structure has not been published. The depositing authors are Brucker, E.A.search

This crystal structure was determined using X-ray diffraction at a resolution of 1.8 Å and deposited in 2002.

The experimental data on which the structure is based was also deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely Hemoglobin Alpha chain and Hemoglobin beta chain.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms heterotrimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Hemoglobin Alpha chain P69905 (2-142) (HBA_HUMAN)search Homo sapienssearch 98% 283 100%
B Hemoglobin beta chain P68871 (2-147) (HBB_HUMAN)search Homo sapienssearch 98% 146 100%
D Hemoglobin beta chain P68871 (2-147) (HBB_HUMAN)search Homo sapienssearch 98% 146 100%


This entry contains 2 unique UniProt proteins:

UniProt accession Name Organism PDB
P69905 (2 - 142) Hemoglobin Alpha chain Homo sapiens
P68871 (2 - 147) Hemoglobin beta chain Homo sapiens

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P69905) Globinssearch Globinssearch PF00042: Globinsearch
B, D (P68871) Globinssearch Globinssearch PF00042: Globinsearch

Chain ID Molecular function (GO) Cellular component (GO) Biological process (GO)
A (P69905) heme bindingsearch protein bindingsearch metal ion bindingsearch peroxidase activitysearch iron ion bindingsearch oxygen bindingsearch oxygen transporter activitysearch haptoglobin bindingsearch extracellular vesicular exosomesearch membranesearch cytosolic small ribosomal subunitsearch extracellular regionsearch blood microparticlesearch hemoglobin complexsearch cytosolsearch endocytic vesicle lumensearch haptoglobin-hemoglobin complexsearch small molecule metabolic processsearch bicarbonate transportsearch oxygen transportsearch response to hydrogen peroxidesearch positive regulation of cell deathsearch hydrogen peroxide catabolic processsearch oxidation-reduction processsearch protein heterooligomerizationsearch transportsearch receptor-mediated endocytosissearch
B, D (P68871) protein bindingsearch hemoglobin bindingsearch oxygen transporter activitysearch oxygen bindingsearch iron ion bindingsearch heme bindingsearch metal ion bindingsearch peroxidase activitysearch haptoglobin bindingsearch blood microparticlesearch extracellular vesicular exosomesearch cytosolsearch hemoglobin complexsearch extracellular regionsearch endocytic vesicle lumensearch haptoglobin-hemoglobin complexsearch oxygen transportsearch response to hydrogen peroxidesearch nitric oxide transportsearch platelet aggregationsearch regulation of blood vessel sizesearch blood coagulationsearch small molecule metabolic processsearch transportsearch positive regulation of cell deathsearch hydrogen peroxide catabolic processsearch protein heterooligomerizationsearch receptor-mediated endocytosissearch renal absorptionsearch oxidation-reduction processsearch regulation of blood pressuresearch bicarbonate transportsearch positive regulation of nitric oxide biosynthetic processsearch

Chain InterPro annotation
A Globinsearch Haemoglobin, alphasearch Haemoglobin, pisearch Globin-likesearch Globin, structural domainsearch
B, D Globinsearch Haemoglobin, betasearch Globin-likesearch Globin, structural domainsearch