1o1p Summary

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Deoxy hemoglobin (A-GLY-C:V1M; B,D:V1M,C93A,N108K)

The structure has not been published. The depositing authors are Brucker, E.A.search

This crystal structure was determined using X-ray diffraction at a resolution of 1.8 Å and deposited in 2002.

The experimental data on which the structure is based was also deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely Hemoglobin Alpha chain and Hemoglobin beta chain.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms heterotrimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Hemoglobin Alpha chain P69905 (2-142) (HBA_HUMAN)search Homo sapienssearch 98% 283 100%
B Hemoglobin beta chain P68871 (2-147) (HBB_HUMAN)search Homo sapienssearch 98% 146 100%
D Hemoglobin beta chain P68871 (2-147) (HBB_HUMAN)search Homo sapienssearch 98% 146 100%


This entry contains 2 unique UniProt proteins:

UniProt accession Name Organism PDB
P69905 (2 - 142) Hemoglobin Alpha chain Homo sapiens
P68871 (2 - 147) Hemoglobin beta chain Homo sapiens

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P69905) Globinssearch Globinssearch PF00042: Globinsearch
B, D (P68871) Globinssearch Globinssearch PF00042: Globinsearch

Chain ID Molecular function (GO) Cellular component (GO) Biological process (GO)
A (P69905) oxygen bindingsearch iron ion bindingsearch protein bindingsearch oxygen transporter activitysearch haptoglobin bindingsearch metal ion bindingsearch heme bindingsearch peroxidase activitysearch extracellular regionsearch hemoglobin complexsearch haptoglobin-hemoglobin complexsearch cytosolsearch endocytic vesicle lumensearch extracellular vesicular exosomesearch membranesearch cytosolic small ribosomal subunitsearch blood microparticlesearch transportsearch positive regulation of cell deathsearch response to hydrogen peroxidesearch oxidation-reduction processsearch hydrogen peroxide catabolic processsearch oxygen transportsearch bicarbonate transportsearch protein heterooligomerizationsearch small molecule metabolic processsearch
B, D (P68871) haptoglobin bindingsearch metal ion bindingsearch protein bindingsearch oxygen bindingsearch oxygen transporter activitysearch heme bindingsearch hemoglobin bindingsearch iron ion bindingsearch peroxidase activitysearch extracellular regionsearch hemoglobin complexsearch extracellular vesicular exosomesearch blood microparticlesearch cytosolsearch haptoglobin-hemoglobin complexsearch endocytic vesicle lumensearch bicarbonate transportsearch oxidation-reduction processsearch renal absorptionsearch oxygen transportsearch transportsearch platelet aggregationsearch nitric oxide transportsearch regulation of blood vessel sizesearch positive regulation of nitric oxide biosynthetic processsearch response to hydrogen peroxidesearch protein heterooligomerizationsearch blood coagulationsearch positive regulation of cell deathsearch hydrogen peroxide catabolic processsearch small molecule metabolic processsearch regulation of blood pressuresearch

Chain InterPro annotation
A Globinsearch Haemoglobin, alphasearch Haemoglobin, pisearch Globin-likesearch Globin, structural domainsearch
B, D Globinsearch Haemoglobin, betasearch Globin-likesearch Globin, structural domainsearch