1o1n Summary

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Deoxy hemoglobin (A-GLYGLYGLY-C:V1M,L29W; B,D:V1M)

The structure has not been published. The depositing authors are Brucker, E.A.search

This crystal structure was determined using X-ray diffraction at a resolution of 1.8 Å and deposited in 2002.

The experimental data on which the structure is based was also deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely Hemoglobin Alpha chain and Hemoglobin beta chain.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms heterotrimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Hemoglobin Alpha chain P69905 (2-142) (HBA_HUMAN)search Homo sapienssearch 98% 285 98%
B Hemoglobin beta chain P68871 (2-147) (HBB_HUMAN)search Homo sapienssearch 98% 146 100%
D Hemoglobin beta chain P68871 (2-147) (HBB_HUMAN)search Homo sapienssearch 98% 146 100%


This entry contains 2 unique UniProt proteins:

UniProt accession Name Organism PDB
P69905 (2 - 142) Hemoglobin Alpha chain Homo sapiens
P68871 (2 - 147) Hemoglobin beta chain Homo sapiens

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P69905) Globinssearch Globinssearch PF00042: Globinsearch
B, D (P68871) Globinssearch Globinssearch PF00042: Globinsearch

Chain ID Molecular function (GO) Biological process (GO) Cellular component (GO)
A (P69905) iron ion bindingsearch heme bindingsearch metal ion bindingsearch protein bindingsearch peroxidase activitysearch haptoglobin bindingsearch oxygen transporter activitysearch oxygen bindingsearch oxygen transportsearch transportsearch small molecule metabolic processsearch oxidation-reduction processsearch bicarbonate transportsearch hydrogen peroxide catabolic processsearch positive regulation of cell deathsearch response to hydrogen peroxidesearch protein heterooligomerizationsearch extracellular vesicular exosomesearch hemoglobin complexsearch membranesearch extracellular regionsearch cytosolsearch blood microparticlesearch cytosolic small ribosomal subunitsearch haptoglobin-hemoglobin complexsearch endocytic vesicle lumensearch
B, D (P68871) oxygen bindingsearch peroxidase activitysearch protein bindingsearch oxygen transporter activitysearch hemoglobin bindingsearch metal ion bindingsearch haptoglobin bindingsearch heme bindingsearch iron ion bindingsearch positive regulation of cell deathsearch oxygen transportsearch blood coagulationsearch regulation of blood pressuresearch transportsearch hydrogen peroxide catabolic processsearch regulation of blood vessel sizesearch renal absorptionsearch response to hydrogen peroxidesearch bicarbonate transportsearch protein heterooligomerizationsearch nitric oxide transportsearch platelet aggregationsearch oxidation-reduction processsearch small molecule metabolic processsearch positive regulation of nitric oxide biosynthetic processsearch extracellular vesicular exosomesearch cytosolsearch hemoglobin complexsearch blood microparticlesearch extracellular regionsearch haptoglobin-hemoglobin complexsearch endocytic vesicle lumensearch

Chain InterPro annotation
A Globinsearch Haemoglobin, alphasearch Haemoglobin, pisearch Globin-likesearch Globin, structural domainsearch
B, D Globinsearch Haemoglobin, betasearch Globin-likesearch Globin, structural domainsearch