1o1n Summary

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Deoxy hemoglobin (A-GLYGLYGLY-C:V1M,L29W; B,D:V1M)

The structure has not been published. The depositing authors are Brucker, E.A.search

This crystal structure was determined using X-ray diffraction at a resolution of 1.8 Å and deposited in 2002.

The experimental data on which the structure is based was also deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely Hemoglobin Alpha chain and Hemoglobin beta chain.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms heterotrimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Hemoglobin Alpha chain P69905 (2-142) (HBA_HUMAN)search Homo sapienssearch 98% 285 98%
B Hemoglobin beta chain P68871 (2-147) (HBB_HUMAN)search Homo sapienssearch 98% 146 100%
D Hemoglobin beta chain P68871 (2-147) (HBB_HUMAN)search Homo sapienssearch 98% 146 100%


This entry contains 2 unique UniProt proteins:

UniProt accession Name Organism PDB
P69905 (2 - 142) Hemoglobin Alpha chain Homo sapiens
P68871 (2 - 147) Hemoglobin beta chain Homo sapiens

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P69905) Globinssearch Globinssearch PF00042: Globinsearch
B, D (P68871) Globinssearch Globinssearch PF00042: Globinsearch

Chain ID Cellular component (GO) Molecular function (GO) Biological process (GO)
A (P69905) hemoglobin complexsearch extracellular vesicular exosomesearch cytosolsearch extracellular regionsearch membranesearch blood microparticlesearch endocytic vesicle lumensearch haptoglobin-hemoglobin complexsearch cytosolic small ribosomal subunitsearch heme bindingsearch oxygen bindingsearch iron ion bindingsearch peroxidase activitysearch protein bindingsearch haptoglobin bindingsearch oxygen transporter activitysearch metal ion bindingsearch oxygen transportsearch oxidation-reduction processsearch small molecule metabolic processsearch transportsearch bicarbonate transportsearch protein heterooligomerizationsearch response to hydrogen peroxidesearch positive regulation of cell deathsearch hydrogen peroxide catabolic processsearch
B, D (P68871) hemoglobin complexsearch cytosolsearch extracellular vesicular exosomesearch blood microparticlesearch extracellular regionsearch haptoglobin-hemoglobin complexsearch endocytic vesicle lumensearch oxygen bindingsearch heme bindingsearch iron ion bindingsearch protein bindingsearch peroxidase activitysearch oxygen transporter activitysearch hemoglobin bindingsearch metal ion bindingsearch haptoglobin bindingsearch oxygen transportsearch regulation of blood pressuresearch positive regulation of cell deathsearch oxidation-reduction processsearch hydrogen peroxide catabolic processsearch blood coagulationsearch small molecule metabolic processsearch nitric oxide transportsearch positive regulation of nitric oxide biosynthetic processsearch bicarbonate transportsearch protein heterooligomerizationsearch regulation of blood vessel sizesearch response to hydrogen peroxidesearch transportsearch renal absorptionsearch

Chain InterPro annotation
A Globinsearch Haemoglobin, alphasearch Haemoglobin, pisearch Globin-likesearch Globin, structural domainsearch
B, D Globinsearch Haemoglobin, betasearch Globin-likesearch Globin, structural domainsearch