1o1n Summary

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Deoxy hemoglobin (A-GLYGLYGLY-C:V1M,L29W; B,D:V1M)

The structure has not been published. The depositing authors are Brucker, E.A.search

This crystal structure was determined using X-ray diffraction at a resolution of 1.8 Å and deposited in 2002.

The experimental data on which the structure is based was also deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely Hemoglobin Alpha chain and Hemoglobin beta chain.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms heterotrimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Hemoglobin Alpha chain P69905 (2-142) (HBA_HUMAN)search Homo sapienssearch 98% 285 98%
B Hemoglobin beta chain P68871 (2-147) (HBB_HUMAN)search Homo sapienssearch 98% 146 100%
D Hemoglobin beta chain P68871 (2-147) (HBB_HUMAN)search Homo sapienssearch 98% 146 100%


This entry contains 2 unique UniProt proteins:

UniProt accession Name Organism PDB
P69905 (2 - 142) Hemoglobin Alpha chain Homo sapiens
P68871 (2 - 147) Hemoglobin beta chain Homo sapiens

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P69905) Globinssearch Globinssearch PF00042: Globinsearch
B, D (P68871) Globinssearch Globinssearch PF00042: Globinsearch

Chain ID Molecular function (GO) Cellular component (GO) Biological process (GO)
A (P69905) oxygen bindingsearch protein bindingsearch oxygen transporter activitysearch metal ion bindingsearch heme bindingsearch iron ion bindingsearch peroxidase activitysearch haptoglobin bindingsearch extracellular regionsearch extracellular vesicular exosomesearch hemoglobin complexsearch haptoglobin-hemoglobin complexsearch blood microparticlesearch cytosolic small ribosomal subunitsearch cytosolsearch endocytic vesicle lumensearch membranesearch receptor-mediated endocytosissearch bicarbonate transportsearch response to hydrogen peroxidesearch positive regulation of cell deathsearch hydrogen peroxide catabolic processsearch protein heterooligomerizationsearch oxygen transportsearch transportsearch oxidation-reduction processsearch small molecule metabolic processsearch
B, D (P68871) metal ion bindingsearch oxygen bindingsearch oxygen transporter activitysearch protein bindingsearch haptoglobin bindingsearch heme bindingsearch iron ion bindingsearch peroxidase activitysearch hemoglobin bindingsearch cytosolsearch extracellular regionsearch extracellular vesicular exosomesearch endocytic vesicle lumensearch hemoglobin complexsearch blood microparticlesearch haptoglobin-hemoglobin complexsearch protein heterooligomerizationsearch oxygen transportsearch bicarbonate transportsearch renal absorptionsearch response to hydrogen peroxidesearch small molecule metabolic processsearch positive regulation of nitric oxide biosynthetic processsearch regulation of blood vessel sizesearch platelet aggregationsearch nitric oxide transportsearch transportsearch regulation of blood pressuresearch oxidation-reduction processsearch positive regulation of cell deathsearch blood coagulationsearch hydrogen peroxide catabolic processsearch receptor-mediated endocytosissearch

Chain InterPro annotation
A Globinsearch Haemoglobin, alphasearch Haemoglobin, pisearch Globin-likesearch Globin, structural domainsearch
B, D Globinsearch Haemoglobin, betasearch Globin-likesearch Globin, structural domainsearch