1o1l Summary

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Deoxy hemoglobin (A-GLY-C:V1M,L29W,H58Q; B,D:V1M)

The structure has not been published. The depositing authors are Brucker, E.A.search

This crystal structure was determined using X-ray diffraction at a resolution of 1.8 Å and deposited in 2002.

The experimental data on which the structure is based was also deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely Hemoglobin Alpha chain and Hemoglobin Beta chain.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms heterotrimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Hemoglobin Alpha chain P69905 (2-142) (HBA_HUMAN)search Homo sapienssearch 98% 283 100%
B Hemoglobin Beta chain P68871 (2-147) (HBB_HUMAN)search Homo sapienssearch 98% 146 100%
D Hemoglobin Beta chain P68871 (2-147) (HBB_HUMAN)search Homo sapienssearch 98% 146 100%


This entry contains 2 unique UniProt proteins:

UniProt accession Name Organism PDB
P69905 (2 - 142) Hemoglobin Alpha chain Homo sapiens
P68871 (2 - 147) Hemoglobin Beta chain Homo sapiens

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P69905) Globinssearch Globinssearch PF00042: Globinsearch
B, D (P68871) Globinssearch Globinssearch PF00042: Globinsearch

Chain ID Molecular function (GO) Cellular component (GO) Biological process (GO)
A (P69905) protein bindingsearch oxygen bindingsearch metal ion bindingsearch peroxidase activitysearch heme bindingsearch haptoglobin bindingsearch oxygen transporter activitysearch iron ion bindingsearch extracellular vesicular exosomesearch hemoglobin complexsearch membranesearch cytosolic small ribosomal subunitsearch haptoglobin-hemoglobin complexsearch extracellular regionsearch endocytic vesicle lumensearch cytosolsearch blood microparticlesearch oxygen transportsearch oxidation-reduction processsearch hydrogen peroxide catabolic processsearch small molecule metabolic processsearch bicarbonate transportsearch protein heterooligomerizationsearch transportsearch positive regulation of cell deathsearch response to hydrogen peroxidesearch
B, D (P68871) protein bindingsearch peroxidase activitysearch iron ion bindingsearch heme bindingsearch oxygen transporter activitysearch hemoglobin bindingsearch oxygen bindingsearch metal ion bindingsearch haptoglobin bindingsearch hemoglobin complexsearch haptoglobin-hemoglobin complexsearch extracellular regionsearch cytosolsearch extracellular vesicular exosomesearch endocytic vesicle lumensearch blood microparticlesearch positive regulation of nitric oxide biosynthetic processsearch bicarbonate transportsearch regulation of blood pressuresearch protein heterooligomerizationsearch positive regulation of cell deathsearch renal absorptionsearch blood coagulationsearch oxygen transportsearch oxidation-reduction processsearch transportsearch hydrogen peroxide catabolic processsearch nitric oxide transportsearch response to hydrogen peroxidesearch platelet aggregationsearch small molecule metabolic processsearch regulation of blood vessel sizesearch

Chain InterPro annotation
A Globinsearch Haemoglobin, alphasearch Haemoglobin, pisearch Globin-likesearch Globin, structural domainsearch
B, D Globinsearch Haemoglobin, betasearch Globin-likesearch Globin, structural domainsearch