1o1l Summary

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Deoxy hemoglobin (A-GLY-C:V1M,L29W,H58Q; B,D:V1M)

The structure has not been published. The depositing authors are Brucker, E.A.search

This crystal structure was determined using X-ray diffraction at a resolution of 1.8 Å and deposited in 2002.

The experimental data on which the structure is based was also deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely Hemoglobin Alpha chain and Hemoglobin Beta chain.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms heterotrimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Hemoglobin Alpha chain P69905 (2-142) (HBA_HUMAN)search Homo sapienssearch 98% 283 100%
B Hemoglobin Beta chain P68871 (2-147) (HBB_HUMAN)search Homo sapienssearch 98% 146 100%
D Hemoglobin Beta chain P68871 (2-147) (HBB_HUMAN)search Homo sapienssearch 98% 146 100%


This entry contains 2 unique UniProt proteins:

UniProt accession Name Organism PDB
P69905 (2 - 142) Hemoglobin Alpha chain Homo sapiens
P68871 (2 - 147) Hemoglobin Beta chain Homo sapiens

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P69905) Globinssearch Globinssearch PF00042: Globinsearch
B, D (P68871) Globinssearch Globinssearch PF00042: Globinsearch

Chain ID Cellular component (GO) Molecular function (GO) Biological process (GO)
A (P69905) hemoglobin complexsearch extracellular regionsearch cytosolsearch extracellular vesicular exosomesearch blood microparticlesearch membranesearch haptoglobin-hemoglobin complexsearch cytosolic small ribosomal subunitsearch endocytic vesicle lumensearch heme bindingsearch protein bindingsearch haptoglobin bindingsearch iron ion bindingsearch oxygen bindingsearch peroxidase activitysearch oxygen transporter activitysearch metal ion bindingsearch bicarbonate transportsearch oxygen transportsearch transportsearch oxidation-reduction processsearch receptor-mediated endocytosissearch small molecule metabolic processsearch hydrogen peroxide catabolic processsearch protein heterooligomerizationsearch positive regulation of cell deathsearch response to hydrogen peroxidesearch
B, D (P68871) extracellular vesicular exosomesearch extracellular regionsearch hemoglobin complexsearch cytosolsearch blood microparticlesearch haptoglobin-hemoglobin complexsearch endocytic vesicle lumensearch iron ion bindingsearch protein bindingsearch oxygen transporter activitysearch hemoglobin bindingsearch haptoglobin bindingsearch oxygen bindingsearch heme bindingsearch metal ion bindingsearch peroxidase activitysearch oxygen transportsearch bicarbonate transportsearch hydrogen peroxide catabolic processsearch renal absorptionsearch small molecule metabolic processsearch response to hydrogen peroxidesearch platelet aggregationsearch regulation of blood pressuresearch oxidation-reduction processsearch nitric oxide transportsearch positive regulation of nitric oxide biosynthetic processsearch receptor-mediated endocytosissearch blood coagulationsearch protein heterooligomerizationsearch positive regulation of cell deathsearch regulation of blood vessel sizesearch transportsearch

Chain InterPro annotation
A Globinsearch Haemoglobin, alphasearch Haemoglobin, pisearch Globin-likesearch Globin, structural domainsearch
B, D Globinsearch Haemoglobin, betasearch Globin-likesearch Globin, structural domainsearch