1o1j Summary

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Deoxy hemoglobin (A-GLY-C:V1M,L29F,H58Q; B,D:V1M,L106W)

The structure has not been published. The depositing authors are Brucker, E.A.search

This crystal structure was determined using X-ray diffraction at a resolution of 1.9 Å and deposited in 2002.

The experimental data on which the structure is based was also deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely Hemoglobin Alpha chain and Hemoglobin Beta chain.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms heterotrimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Hemoglobin Alpha chain P69905 (2-142) (HBA_HUMAN)search Homo sapienssearch 98% 283 100%
B Hemoglobin Beta chain P68871 (2-147) (HBB_HUMAN)search Homo sapienssearch 98% 146 100%
D Hemoglobin Beta chain P68871 (2-147) (HBB_HUMAN)search Homo sapienssearch 98% 146 100%


This entry contains 2 unique UniProt proteins:

UniProt accession Name Organism PDB
P69905 (2 - 142) Hemoglobin Alpha chain Homo sapiens
P68871 (2 - 147) Hemoglobin Beta chain Homo sapiens

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P69905) Globinssearch Globinssearch PF00042: Globinsearch
B, D (P68871) Globinssearch Globinssearch PF00042: Globinsearch

Chain ID Biological process (GO) Molecular function (GO) Cellular component (GO)
A (P69905) oxygen transportsearch oxidation-reduction processsearch positive regulation of cell deathsearch response to hydrogen peroxidesearch protein heterooligomerizationsearch small molecule metabolic processsearch bicarbonate transportsearch hydrogen peroxide catabolic processsearch transportsearch protein bindingsearch oxygen transporter activitysearch heme bindingsearch haptoglobin bindingsearch oxygen bindingsearch metal ion bindingsearch iron ion bindingsearch peroxidase activitysearch extracellular vesicular exosomesearch extracellular regionsearch membranesearch hemoglobin complexsearch cytosolsearch endocytic vesicle lumensearch haptoglobin-hemoglobin complexsearch blood microparticlesearch cytosolic small ribosomal subunitsearch
B, D (P68871) oxygen transportsearch renal absorptionsearch bicarbonate transportsearch nitric oxide transportsearch hydrogen peroxide catabolic processsearch regulation of blood pressuresearch positive regulation of nitric oxide biosynthetic processsearch transportsearch blood coagulationsearch protein heterooligomerizationsearch response to hydrogen peroxidesearch oxidation-reduction processsearch small molecule metabolic processsearch positive regulation of cell deathsearch regulation of blood vessel sizesearch platelet aggregationsearch haptoglobin bindingsearch protein bindingsearch metal ion bindingsearch oxygen bindingsearch hemoglobin bindingsearch oxygen transporter activitysearch iron ion bindingsearch peroxidase activitysearch heme bindingsearch hemoglobin complexsearch endocytic vesicle lumensearch extracellular vesicular exosomesearch cytosolsearch haptoglobin-hemoglobin complexsearch extracellular regionsearch blood microparticlesearch

Chain InterPro annotation
A Globinsearch Haemoglobin, alphasearch Haemoglobin, pisearch Globin-likesearch Globin, structural domainsearch
B, D Globinsearch Haemoglobin, betasearch Globin-likesearch Globin, structural domainsearch