1o1j Summary

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Deoxy hemoglobin (A-GLY-C:V1M,L29F,H58Q; B,D:V1M,L106W)

The structure has not been published. The depositing authors are Brucker, E.A.search

This crystal structure was determined using X-ray diffraction at a resolution of 1.9 Å and deposited in 2002.

The experimental data on which the structure is based was also deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely Hemoglobin Alpha chain and Hemoglobin Beta chain.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms heterotrimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Hemoglobin Alpha chain P69905 (2-142) (HBA_HUMAN)search Homo sapienssearch 98% 283 100%
B Hemoglobin Beta chain P68871 (2-147) (HBB_HUMAN)search Homo sapienssearch 98% 146 100%
D Hemoglobin Beta chain P68871 (2-147) (HBB_HUMAN)search Homo sapienssearch 98% 146 100%


This entry contains 2 unique UniProt proteins:

UniProt accession Name Organism PDB
P69905 (2 - 142) Hemoglobin Alpha chain Homo sapiens
P68871 (2 - 147) Hemoglobin Beta chain Homo sapiens

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P69905) Globinssearch Globinssearch PF00042: Globinsearch
B, D (P68871) Globinssearch Globinssearch PF00042: Globinsearch

Chain ID Biological process (GO) Molecular function (GO) Cellular component (GO)
A (P69905) oxygen transportsearch oxidation-reduction processsearch response to hydrogen peroxidesearch protein heterooligomerizationsearch small molecule metabolic processsearch transportsearch positive regulation of cell deathsearch hydrogen peroxide catabolic processsearch bicarbonate transportsearch oxygen bindingsearch iron ion bindingsearch protein bindingsearch peroxidase activitysearch metal ion bindingsearch heme bindingsearch haptoglobin bindingsearch oxygen transporter activitysearch cytosolic small ribosomal subunitsearch membranesearch extracellular regionsearch hemoglobin complexsearch endocytic vesicle lumensearch cytosolsearch extracellular vesicular exosomesearch haptoglobin-hemoglobin complexsearch blood microparticlesearch
B, D (P68871) oxygen transportsearch renal absorptionsearch bicarbonate transportsearch hydrogen peroxide catabolic processsearch protein heterooligomerizationsearch blood coagulationsearch regulation of blood vessel sizesearch nitric oxide transportsearch response to hydrogen peroxidesearch positive regulation of nitric oxide biosynthetic processsearch transportsearch positive regulation of cell deathsearch small molecule metabolic processsearch regulation of blood pressuresearch oxidation-reduction processsearch heme bindingsearch iron ion bindingsearch oxygen bindingsearch protein bindingsearch haptoglobin bindingsearch metal ion bindingsearch hemoglobin bindingsearch oxygen transporter activitysearch peroxidase activitysearch extracellular regionsearch endocytic vesicle lumensearch hemoglobin complexsearch extracellular vesicular exosomesearch cytosolsearch blood microparticlesearch haptoglobin-hemoglobin complexsearch

Chain InterPro annotation
A Globinsearch Haemoglobin, alphasearch Haemoglobin, pisearch Globin-likesearch Globin, structural domainsearch
B, D Globinsearch Haemoglobin, betasearch Globin-likesearch Globin, structural domainsearch