1o1i Summary

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Cyanomet hemoglobin (A-GLY-C:V1M,L29F,H58Q; B,D:V1M,L106W)

The structure has not been published. The depositing authors are Brucker, E.A.search

This crystal structure was determined using X-ray diffraction at a resolution of 2.3 Å and deposited in 2002.

The experimental data on which the structure is based was also deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely Hemoglobin Alpha chain and Hemoglobin Beta chain.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms heterotetramers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Hemoglobin Alpha chain P69905 (2-142) (HBA_HUMAN)search Homo sapienssearch 98% 141 100%
B Hemoglobin Beta chain P68871 (2-147) (HBB_HUMAN)search Homo sapienssearch 98% 146 100%


This entry contains 2 unique UniProt proteins:

UniProt accession Name Organism PDB
P69905 (2 - 142) Hemoglobin Alpha chain Homo sapiens
P68871 (2 - 147) Hemoglobin Beta chain Homo sapiens

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P69905) Globinssearch Globinssearch PF00042: Globinsearch
B (P68871) Globinssearch Globinssearch PF00042: Globinsearch

Chain ID Molecular function (GO) Biological process (GO) Cellular component (GO)
A (P69905) iron ion bindingsearch heme bindingsearch oxygen bindingsearch protein bindingsearch metal ion bindingsearch oxygen transporter activitysearch haptoglobin bindingsearch peroxidase activitysearch oxygen transportsearch bicarbonate transportsearch positive regulation of cell deathsearch small molecule metabolic processsearch oxidation-reduction processsearch receptor-mediated endocytosissearch transportsearch hydrogen peroxide catabolic processsearch protein heterooligomerizationsearch response to hydrogen peroxidesearch hemoglobin complexsearch extracellular exosomesearch blood microparticlesearch membranesearch cytosolsearch cytosolic small ribosomal subunitsearch extracellular regionsearch endocytic vesicle lumensearch haptoglobin-hemoglobin complexsearch
B (P68871) iron ion bindingsearch heme bindingsearch oxygen transporter activitysearch protein bindingsearch metal ion bindingsearch haptoglobin bindingsearch oxygen bindingsearch peroxidase activitysearch hemoglobin bindingsearch regulation of blood pressuresearch renal absorptionsearch platelet aggregationsearch oxygen transportsearch positive regulation of cell deathsearch protein heterooligomerizationsearch receptor-mediated endocytosissearch blood coagulationsearch bicarbonate transportsearch positive regulation of nitric oxide biosynthetic processsearch nitric oxide transportsearch small molecule metabolic processsearch oxidation-reduction processsearch response to hydrogen peroxidesearch hydrogen peroxide catabolic processsearch transportsearch regulation of blood vessel sizesearch hemoglobin complexsearch extracellular regionsearch extracellular exosomesearch cytosolsearch haptoglobin-hemoglobin complexsearch blood microparticlesearch endocytic vesicle lumensearch

Chain InterPro annotation
A Globinsearch Haemoglobin, alphasearch Haemoglobin, pisearch Globin-likesearch Globin, structural domainsearch
B Globinsearch Haemoglobin, betasearch Globin-likesearch Globin, structural domainsearch