1o1i Summary

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Cyanomet hemoglobin (A-GLY-C:V1M,L29F,H58Q; B,D:V1M,L106W)

The structure has not been published. The depositing authors are Brucker, E.A.search

This crystal structure was determined using X-ray diffraction at a resolution of 2.3 Å and deposited in 2002.

The experimental data on which the structure is based was also deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely Hemoglobin Alpha chain and Hemoglobin Beta chain.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms heterotetramers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Hemoglobin Alpha chain P69905 (2-142) (HBA_HUMAN)search Homo sapienssearch 98% 141 100%
B Hemoglobin Beta chain P68871 (2-147) (HBB_HUMAN)search Homo sapienssearch 98% 146 100%


This entry contains 2 unique UniProt proteins:

UniProt accession Name Organism PDB
P69905 (2 - 142) Hemoglobin Alpha chain Homo sapiens
P68871 (2 - 147) Hemoglobin Beta chain Homo sapiens

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P69905) Globinssearch Globinssearch PF00042: Globinsearch
B (P68871) Globinssearch Globinssearch PF00042: Globinsearch

Chain ID Cellular component (GO) Molecular function (GO) Biological process (GO)
A (P69905) cytosolic small ribosomal subunitsearch cytosolsearch hemoglobin complexsearch extracellular vesicular exosomesearch blood microparticlesearch membranesearch extracellular regionsearch endocytic vesicle lumensearch haptoglobin-hemoglobin complexsearch protein bindingsearch oxygen transporter activitysearch metal ion bindingsearch heme bindingsearch haptoglobin bindingsearch peroxidase activitysearch iron ion bindingsearch oxygen bindingsearch oxidation-reduction processsearch positive regulation of cell deathsearch small molecule metabolic processsearch oxygen transportsearch hydrogen peroxide catabolic processsearch transportsearch response to hydrogen peroxidesearch bicarbonate transportsearch protein heterooligomerizationsearch
B (P68871) extracellular vesicular exosomesearch extracellular regionsearch cytosolsearch hemoglobin complexsearch haptoglobin-hemoglobin complexsearch endocytic vesicle lumensearch blood microparticlesearch iron ion bindingsearch oxygen bindingsearch protein bindingsearch metal ion bindingsearch heme bindingsearch oxygen transporter activitysearch haptoglobin bindingsearch hemoglobin bindingsearch peroxidase activitysearch nitric oxide transportsearch renal absorptionsearch blood coagulationsearch bicarbonate transportsearch transportsearch positive regulation of cell deathsearch protein heterooligomerizationsearch positive regulation of nitric oxide biosynthetic processsearch oxygen transportsearch response to hydrogen peroxidesearch small molecule metabolic processsearch hydrogen peroxide catabolic processsearch oxidation-reduction processsearch regulation of blood vessel sizesearch regulation of blood pressuresearch platelet aggregationsearch

Chain InterPro annotation
A Globinsearch Haemoglobin, alphasearch Haemoglobin, pisearch Globin-likesearch Globin, structural domainsearch
B Globinsearch Haemoglobin, betasearch Globin-likesearch Globin, structural domainsearch