1o1i Summary

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Cyanomet hemoglobin (A-GLY-C:V1M,L29F,H58Q; B,D:V1M,L106W)

The structure has not been published. The depositing authors are Brucker, E.A.search

This crystal structure was determined using X-ray diffraction at a resolution of 2.3 Å and deposited in 2002.

The experimental data on which the structure is based was also deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely Hemoglobin Alpha chain and Hemoglobin Beta chain.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms heterotetramers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Hemoglobin Alpha chain P69905 (2-142) (HBA_HUMAN)search Homo sapienssearch 98% 141 100%
B Hemoglobin Beta chain P68871 (2-147) (HBB_HUMAN)search Homo sapienssearch 98% 146 100%


This entry contains 2 unique UniProt proteins:

UniProt accession Name Organism PDB
P69905 (2 - 142) Hemoglobin Alpha chain Homo sapiens
P68871 (2 - 147) Hemoglobin Beta chain Homo sapiens

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P69905) Globinssearch Globinssearch PF00042: Globinsearch
B (P68871) Globinssearch Globinssearch PF00042: Globinsearch

Chain ID Molecular function (GO) Biological process (GO) Cellular component (GO)
A (P69905) heme bindingsearch oxygen bindingsearch protein bindingsearch oxygen transporter activitysearch iron ion bindingsearch haptoglobin bindingsearch metal ion bindingsearch peroxidase activitysearch bicarbonate transportsearch small molecule metabolic processsearch positive regulation of cell deathsearch oxygen transportsearch hydrogen peroxide catabolic processsearch transportsearch protein heterooligomerizationsearch response to hydrogen peroxidesearch oxidation-reduction processsearch blood microparticlesearch hemoglobin complexsearch extracellular vesicular exosomesearch membranesearch cytosolsearch cytosolic small ribosomal subunitsearch extracellular regionsearch endocytic vesicle lumensearch haptoglobin-hemoglobin complexsearch
B (P68871) protein bindingsearch oxygen transporter activitysearch metal ion bindingsearch iron ion bindingsearch haptoglobin bindingsearch hemoglobin bindingsearch peroxidase activitysearch oxygen bindingsearch heme bindingsearch oxygen transportsearch platelet aggregationsearch renal absorptionsearch positive regulation of nitric oxide biosynthetic processsearch regulation of blood vessel sizesearch positive regulation of cell deathsearch protein heterooligomerizationsearch bicarbonate transportsearch blood coagulationsearch nitric oxide transportsearch regulation of blood pressuresearch oxidation-reduction processsearch response to hydrogen peroxidesearch transportsearch hydrogen peroxide catabolic processsearch small molecule metabolic processsearch extracellular regionsearch extracellular vesicular exosomesearch cytosolsearch hemoglobin complexsearch haptoglobin-hemoglobin complexsearch endocytic vesicle lumensearch blood microparticlesearch

Chain InterPro annotation
A Globinsearch Haemoglobin, alphasearch Haemoglobin, pisearch Globin-likesearch Globin, structural domainsearch
B Globinsearch Haemoglobin, betasearch Globin-likesearch Globin, structural domainsearch