1o0w Summary

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Crystal structure of Ribonuclease III (TM1102) from Thermotoga maritima at 2.0 A resolution

The structure was published by Joint Center for Structural Genomics (JCSG), in in a paper entitled "Crystal structure of Ribonuclease III (TM1102) from Thermotoga maritima at 2.0 A resolution" (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.0 Å and deposited in 2002.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of Ribonuclease III.

The molecule most likely forms homodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Ribonuclease III Q9X0I6 (1-240) (RNC_THEMA)search Thermotoga maritima MSB8search 100% 252 94%
B Ribonuclease III Q9X0I6 (1-240) (RNC_THEMA)search Thermotoga maritima MSB8search 100% 252 94%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q9X0I6 (1 - 240) Ribonuclease III Thermotoga maritima

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B (Q9X0I6) RNase III catalytic domain-likesearch, Double-stranded RNA-binding domain (dsRBD)search Ribonuclease iii, N-terminal Endonuclease Domain; Chain Asearch, Double Stranded RNA Binding Domainsearch PF00035: Double-stranded RNA binding motifsearch, PF14622: Ribonuclease-III-likesearch

Chain ID Biological process (GO) Molecular function (GO) Cellular component (GO)
A, B (Q9X0I6) RNA processingsearch RNA phosphodiester bond hydrolysis, endonucleolyticsearch rRNA catabolic processsearch RNA phosphodiester bond hydrolysissearch rRNA processingsearch mRNA processingsearch nucleic acid phosphodiester bond hydrolysissearch tRNA processingsearch RNA bindingsearch ribonuclease III activitysearch metal ion bindingsearch rRNA bindingsearch hydrolase activitysearch endonuclease activitysearch nuclease activitysearch cytoplasmsearch

Chain InterPro annotation
A, B Ribonuclease III domainsearch Ribonuclease IIIsearch Double-stranded RNA-binding domainsearch