spacer
EBI PDBe PDBeView

PDBe Entry: 1nw4 view

Crystal Structure of Plasmodium falciparum Purine Nucleoside Phosphorylase in complex with ImmH and Sulfate
Summary
Header Transferasesearch
Method X-RAY DIFFRACTION
Experiment Resolution: 2.2 Å, R-factor: 20.9%, Free R-factor: 24.8%, Spacegroup: P 21 21 21
Released 16/03/2004, deposition: 05/02/2003, last revision: 24/02/2009
Authors Shi, W.search; Ting, L.M.search; Kicska, G.A.search; Lewandowicz, A.search; Tyler, P.C.search; Evans, G.B.search; Furneaux, R.H.search; Kim, K.search; Almo, S.C.search; Schramm, V.L.search
Primary citation Plasmodium falciparum Purine Nucleoside Phosphorylase: CRYSTAL STRUCTURES, IMMUCILLIN INHIBITORS, AND DUAL CATALYTIC FUNCTION.
J.BIOL.CHEM.search vol:279, pag:18103-18106 (2004) [PubMed ID 14982926 ]search
Keywords Transition State Complexsearch, Transferasesearch
EC 2.4.2.3 ExPASy BRENDA search (A B C D E F)
Organism Plasmodium falciparum 3D7 36329search(A B C D E F)
UniProt Uridine phosphorylase, putative (EC 2.4.2.3) Q8I3X4search (A B C D E F)
Solvent A, B, C, D, E, F
Polymers
Id Name Type UniProt Residues Observed
A, B, C, D, E, F uridine phosphorylase, putative Protein Q8I3X4 (Q8I3X4_PLAF7)search
 276 88%
Heterogens
Id Name Ligands
A, B, C, D, E, F SULFATE ION SO4 search
A, B, C, D, E, F 1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-D-RIBITOL IMH search
B, A, D, C, F, E ISOPROPYL ALCOHOL IPA search
spacer