1nw1 Summary


Crystal Structure of Choline Kinase

The structure was published by Peisach, D., Gee, P., Kent, C., and Xu, Z., in 2003 in a paper entitled "The Crystal Structure of Choline Kinase Reveals a Eukaryotic Protein Kinase Fold" (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.02 Å and deposited in 2003.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of Choline kinase (49.2 kD).

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms homodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Choline kinase (49.2 kD) Q22942 (1-429) (Q22942_CAEEL)search Caenorhabditis eleganssearch 100% 429 85%
B Choline kinase (49.2 kD) Q22942 (1-429) (Q22942_CAEEL)search Caenorhabditis eleganssearch 100% 429 85%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q22942 (1 - 429) Choline kinase (49.2 kD) Caenorhabditis elegans

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B (Q22942) Choline kinasesearch Choline kinase; domain 1search, Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2search PF01633: Choline/ethanolamine kinasesearch

Chain ID Biological process (GO) Molecular function (GO)
A, B (Q22942) CDP-choline pathwaysearch transferase activity, transferring phosphorus-containing groupssearch choline kinase activitysearch metal ion bindingsearch

Chain InterPro annotation
A, B Protein kinase-like domainsearch