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EBI PDBe PDBeView

PDBe Entry: 1nu6 view

Crystal structure of human Dipeptidyl Peptidase IV (DPP-IV)
Summary
Header HYDROLASEsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 2.1 Å, R-factor: 21.74%, Free R-factor: 26.56%, Spacegroup: P 21 21 21
Released 26/08/2003, deposition: 31/01/2003, last revision: 24/02/2009
Authors Hennig, M.search; Stihle, M.search; Thoma, R.search; Ruf, A.search
Primary citation Structural Basis of Proline-Specific Exopeptidase Activity as Observed in Human Dipeptidyl Peptidase-IV.
STRUCTUREsearch vol:11, pag:947-959 (2003) [PubMed ID 12906826 ]search
Keywords exopeptidasesearch, beta barrelsearch, alpha/beta hydrolase foldsearch, DPP-IVsearch
EC 3.4.14.5 ExPASy BRENDA search (A B)
Organism Homo sapiens(human) 9606search(A B)
UniProt Dipeptidyl peptidase 4 (EC 3.4.14.5) (Dipeptidyl peptidase IV) (DPP IV) (T-cell activation antigen CD26) (TP103) (Adenosine deaminase complexing protein 2) (ADABP) [Contains: Dipeptidyl peptidase 4 membrane form (Dipeptidyl peptidase IV membrane form); Dipeptidyl peptidase 4 soluble form (Dipeptidyl peptidase IV soluble form)] P27487search (A B)
Solvent A, B
Related entries 1nu8
Polymers
Id Name Type UniProt Residues Observed
A, B Dipeptidyl peptidase IV Protein P27487 (DPP4_HUMAN)search
 728 100%
Heterogens
Id Name Ligands
A, B SUGAR (N-ACETYL-D-GLUCOSAMINE) NAG search
B SUGAR (2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE) NDG search
A, B MERCURY (II) ION HG search
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