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PDBe Entry: 1nou 
Native human lysosomal beta-hexosaminidase isoform B
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HYDROLASE
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X-RAY DIFFRACTION
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Resolution: 2.4 Å, R-factor: 20.266%, Free R-factor: 23.121%, Spacegroup: P 61 2 2
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08/04/2003, deposition: 16/01/2003, last revision: 24/02/2009
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Mark, B.L.; Mahuran, D.J.; Cherney, M.M.; Zhao, D.; Knapp, S.; James, M.N.G.
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Crystal structure of Human beta-hexosaminidase B: Understanding the molecular basis of Sandhoff and Tay-Sachs disease
J.MOL.BIOL. vol:327, pag:1093-1109 (2003) [PubMed ID 12662933 ]
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(beta/alpha)8-barrel, homodimer, family 20 glycosidase, HYDROLASE
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3.2.1.52 ExPASy BRENDA (A B)
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Homo sapiens(human) 9606(A B)
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Beta-hexosaminidase subunit beta precursor (EC 3.2.1.52) (N-acetyl-beta-glucosaminidase subunit beta) (Beta-N-acetylhexosaminidase subunit beta) (Hexosaminidase subunit B) (Cervical cancer proto-oncogene 7 protein) (HCC-7) [Contains: Beta-hexosaminidase subunit beta chain B; Beta-hexosaminidase subunit beta chain A] P07686 (A B)
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A, B
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| A, B |
beta-hexosaminidase beta chain |
Protein |
P07686 (HEXB_HUMAN)
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507 |
94% |
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| A, B |
SUGAR (NAG-NAG) |
NAG
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| B |
SULFATE ION |
SO4
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| A, B |
GLYCEROL |
GOL
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