› 1nn7

X-ray diffraction
2.1Å resolution

Crystal Structure Of The Tetramerization Domain Of The Shal Voltage-Gated Potassium Channel

Released:
DOI: 10.2210/pdb1nn7/pdb
PDB entry 1nn7 coloured by chain, front view.
PDB entry 1nn7 coloured by chain, side view.
PDB entry 1nn7 coloured by chain, top view.
Source organism: Rattus norvegicus
Primary publication:
Determining the basis of channel-tetramerization specificity by x-ray crystallography and a sequence-comparison algorithm: Family Values (FamVal).
Nanao MH, Zhou W, Pfaffinger PJ, Choe S
Proc Natl Acad Sci U S A 100 8670-5 (2003)
PMID: 12835418

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
homo tetramer
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-179038 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Potassium voltage-gated channel subfamily D member 2 Chain: A
Molecule details ›
Chain: A
Length: 105 amino acids
Theoretical weight: 12.79 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q63881 (Residues: 42-146; Coverage: 17%)
Gene name: Kcnd2
Sequence domains: BTB/POZ domain
Structure domains: Potassium Channel Kv1.1; Chain A

Ligands and Environments

1 bound ligand:
Ligand ZN 1 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: MACSCIENCE M18X
Spacegroup: P4212
Unit cell:
a: 59.999Å b: 59.999Å c: 61.593Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.23 0.23 0.277
Expression system: Escherichia coli BL21

Quick links

Citations

4 review citations

Molecular physiology and modulation of somatodendritic A-type potassium channels.
Jerng et al. (2004)
3 more

3 mentions without citation

Pentameric assembly of potassium channel tetramerization domain-containing protein 5.
Dementieva et al. (2009)
2 more