1nkk Summary

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COMPLEX STRUCTURE OF HCMV PROTEASE AND A PEPTIDOMIMETIC INHIBITOR

The structure was published by Khayat, R., Batra, R., Qian, C., Halmos, T., Bailey, M., and Tong, L., in 2003 in a paper entitled "Structural and Biochemical Studies of Inhibitor Binding to Human Cytomegalovirus Protease" (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.6 Å and deposited in 2003.

The experimental data on which the structure is based was not deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely Capsid protein P40 and Peptidomimetic inhibitor.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Capsid protein P40 P16753 (1-256) (SCAF_HCMVA)search Human herpesvirus 5 strain AD169search < 90% 256 88%
B Capsid protein P40 P16753 (1-256) (SCAF_HCMVA)search Human herpesvirus 5 strain AD169search < 90% 256 88%
C Capsid protein P40 P16753 (1-256) (SCAF_HCMVA)search Human herpesvirus 5 strain AD169search < 90% 256 88%
D Capsid protein P40 P16753 (1-256) (SCAF_HCMVA)search Human herpesvirus 5 strain AD169search < 90% 256 88%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P16753 (1 - 256) Capsid protein P40 Human herpesvirus 5

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B, C, D Herpes virus serine proteinase, assemblinsearch Herpes virus serine proteinase, assemblinsearch Assemblin (Peptidase family S21)search

Chain ID Molecular function (GO) Biological process (GO)
A, B, C, D (P16753) serine-type endopeptidase activitysearch proteolysissearch

Chain InterPro annotation
A, B, C, D Peptidase S21search