1nk3 Summary

pdbe.org/1nk3
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VND/NK-2 HOMEODOMAIN/DNA COMPLEX, NMR, MINIMIZED AVERAGE STRUCTURE

The structure was published by Gruschus, J.M., Tsao, D.H., Wang, L.H., Nirenberg, M., and Ferretti, J.A., in 1997 in a paper entitled "Interactions of the vnd/NK-2 homeodomain with DNA by nuclear magnetic resonance spectroscopy: basis of binding specificity." (abstract).

The structure was determined using NMR spectroscopy and deposited in 1998.

The experimental data on which the structure is based was not deposited.

This PDB entry contains a complex of 3 biomacromolecules, namely DNA (5'-D(*TP*GP*TP*GP*TP*CP*AP*AP*GP*TP*GP*GP*CP*TP*GP*T)-3'), DNA (5'-D(*AP*CP*AP*GP*CP*CP*AP*CP*TP*TP*GP*AP*CP*AP*CP*A)-3'), and HOMEOBOX PROTEIN VND.

The molecule most likely forms heterotrimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
P HOMEOBOX PROTEIN VND P22808 (538-606) (VND_DROME)search Drosophila melanogastersearch < 90% 77 81%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P22808 (538 - 606) HOMEOBOX PROTEIN VND Drosophila melanogaster

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
P Homeodomainsearch Homeodomain-likesearch Homeobox domainsearch

Chain ID Biological process (GO) Molecular function (GO) Cellular component (GO)
P (P22808) regulation of transcription, DNA-templatedsearch sequence-specific DNA binding transcription factor activitysearch DNA bindingsearch sequence-specific DNA bindingsearch nucleussearch

Chain InterPro annotation
P Homeobox domainsearch Homeodomain-likesearch Homeobox, conserved sitesearch Homeodomain, metazoasearch