Crystal Structure of the Antagonist Form of Glucocorticoid Receptor
The structure was published by Kauppi, B., Jakob, C., Farnegardh, M., et al., Gustafsson, J.-A., Carlstedt-Duke, J., and Carlquist, M., in 2003 in a paper entitled "The Three-dimensional Structures of Antagonistic and Agonistic Forms of the Glucocorticoid Receptor Ligand-binding Domain: RU-486 INDUCES A TRANSCONFORMATION THAT LEADS TO ACTIVE ANTAGONISM." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.3 Å and deposited in 2002.
The experimental data on which the structure is based was also deposited.
The PDB entry contains the structure of GLUCOCORTICOID RECEPTOR. This molecule has the UniProt identifier P04150 (GCR_HUMAN). The sample contained 280 residues which is < 90% of the natural sequence. Out of 280 residues 239 were observed and are deposited in the PDB.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: