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EBI PDBe PDBeView

PDBe Entry: 1ngs view

COMPLEX OF TRANSKETOLASE WITH THIAMIN DIPHOSPHATE, CA2+ AND ACCEPTOR SUBSTRATE ERYTHROSE-4-PHOSPHATE
Summary
Header TRANSFERASEsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 2.4 Å, R-factor: 20.6%, Free R-factor: 23.9%, Spacegroup: P 21 21 21
Released 12/02/1997, deposition: 25/09/1996, last revision: 24/02/2009
Authors Nilsson, U.search; Lindqvist, Y.search; Schneider, G.search
Primary citation Examination of substrate binding in thiamin diphosphate-dependent transketolase by protein crystallography and site-directed mutagenesis.
J.BIOL.CHEM.search vol:272, pag:1864-1869 (1997) [PubMed ID 8999873 ]search
Keywords TRANSFERASEsearch, THIAMINE PYROPHOSPHATEsearch, MAGNESIUMsearch, MULTIGENE FAMILYsearch
EC 2.2.1.1 ExPASy BRENDA search (A B)
Organism Saccharomyces cerevisiae(baker's yeast) 4932search(A B)
UniProt Transketolase 1 (EC 2.2.1.1) (TK 1) P23254search (A B)
Solvent A, B
Polymers
Id Name Type UniProt Residues Observed
A, B TRANSKETOLASE Protein P23254 (TKT1_YEAST)search
 680 99%
Heterogens
Id Name Ligands
A, B CALCIUM ION CA search
A, B ERYTHOSE-4-PHOSPHATE E4P search
A, B THIAMINE DIPHOSPHATE TPP search
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